Literature DB >> 16469377

Translocation (13;17)(q14;q25) as a novel chromosomal abnormality in acute myeloid leukemia-M4.

Nihan Turhan1, Nüket Yürür-Kutlay, Pervin Topcuoglu, Müyesser Sayki, Meltem Yüksel, Günhan Gürman, Ajlan Tükün.   

Abstract

We report a case of AML-M4 in which G-band karyotyping revealed a previously unreported t(13;17)(q14;q25) in metaphase preparations. The breakpoints at 13q14 and 17q25 are associated with poor prognosis. The MSF and FKHR genes are located on 17q25 and 13q14, respectively. This report of AML-M4 harboring t(13;17)(q14;q25) as a unique cytogenetic abnormality provides more data on the leukomogenesis with rearrangements related with 13q14 and 17q25.

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Year:  2006        PMID: 16469377     DOI: 10.1016/j.leukres.2005.12.011

Source DB:  PubMed          Journal:  Leuk Res        ISSN: 0145-2126            Impact factor:   3.156


  5 in total

1.  Duplication of Subcytoband 11E2 of Chromosome 11 Is Regularly Associated with Accelerated Tumor Development in v-abl/myc-Induced Mouse Plasmacytomas.

Authors:  Francis Wiener; Ann-Kristin Schmälter; Michael R A Mowat; Sabine Mai
Journal:  Genes Cancer       Date:  2010-08

2.  AML1 amplification and 17q25 deletion in a case of childhood acute lymphoblastic leukemia.

Authors:  Tuna Gulten; Tahsin Yakut; Mutlu Karkucak; Birol Baytan; Adalet Meral Guneş
Journal:  J Clin Lab Anal       Date:  2009       Impact factor: 2.352

3.  Selected telomere length changes and aberrant three-dimensional nuclear telomere organization during fast-onset mouse plasmacytomas.

Authors:  Alexandra Kuzyk; Sabine Mai
Journal:  Neoplasia       Date:  2012-04       Impact factor: 5.715

4.  Changes in Nuclear Orientation Patterns of Chromosome 11 during Mouse Plasmacytoma Development.

Authors:  Ann-Kristin Schmälter; Christiaan H Righolt; Alexandra Kuzyk; Sabine Mai
Journal:  Transl Oncol       Date:  2015-10       Impact factor: 4.243

5.  B-cell Acute Lymphoblastic Leukemia With t(9;22)(q34;q11) Translocation and Clonal Divergence Through ider(22) Chromosome and t(13;17)(q14;q25) Translocation.

Authors:  Juan Pablo Meza-Espinoza; Enrique Jhonatan Romo Martínez; Lilia Aguilar López; Verónica Judith Picos Cárdenas; María Teresa Magaña Torres; Juan Ramón González García
Journal:  Ann Lab Med       Date:  2016-03       Impact factor: 3.464

  5 in total

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