Literature DB >> 16469084

Granulomas induced by subcutaneous injection of leuprorelin acetate.

Ryoko Sakamoto1, Yuko Higashi, Kentaro Mera, Takuro Kanekura, Tamotsu Kanzaki.   

Abstract

Leuprorelin acetate, a chemotherapeutic agent used to treat prostate cancer, is a synthetic luteinizing hormone-releasing hormone (LHRH) agonist. We report a 75-year-old man who presented with several large subcutaneous nodules at the site of leuprorelin acetate injections for his prostatic cancer. A biopsy of the nodules disclosed epithelioid granulomatous inflammation and resulted in a diagnosis of drug-induced granulomatous reaction to leuprorelin acetate.

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Year:  2006        PMID： 16469084     DOI： 10.1111/j.1346-8138.2006.00008.x

Source DB:  PubMed          Journal:  J Dermatol        ISSN： 0385-2407            Impact factor:   4.005


  5 in total

1.  Imaging of recurrent intramuscular granulomatous masses induced by depot injection of leuprorelin.

Authors:  Emily N Vinson; Andresa Braga-Baiak; Leslie G Dodd; Salutario Martinez
Journal:  Skeletal Radiol       Date:  2011-08-23       Impact factor: 2.199

2.  Evaluation of histopathological findings at the injection site following degarelix administration.

Authors:  Takahiro Maeda; Takeo Kosaka; Aki Honda; Utako Okata; Nozomi Hayakawa; Yujiro Ito; Hirohiko Nagata; Ko-Ron Chen; So Nakamura; Mototsugu Oya
Journal:  Support Care Cancer       Date:  2014-10-31       Impact factor: 3.603

3.  Supraventricular tachycardia and urticaria complicating leuprolide-induced ovarian suppression in a young woman with breast cancer: a case report.

Authors:  Sharan Prakash Sharma; Franco Muggia
Journal:  Ecancermedicalscience       Date:  2013-07-24

4.  Bilateral injection-site granuloma by subcutaneous administration of luteinizing hormone-releasing hormone analogue: a case report.

Authors:  Riko Kitazawa; Fukashi Yamamichi; Toshiharu Hidaka; Shinichi Morishita; Takeshi Kondo; Kiyoshi Mori; Sohei Kitazawa
Journal:  Cases J       Date:  2009-09-15

5.  Foreign body granulomas induced by intramuscular leuprorelin acetate injection for prostate cancer: clinical mimics of soft tissue sarcoma.

Authors:  Khin Thway; Dirk C Strauss; Myles J Smith; Cyril Fisher
Journal:  Case Rep Oncol Med       Date:  2015-03-31
  5 in total

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