Literature DB >> 16466752

Endemic threshold results in an age-duration-structured population model for HIV infection.

Hisashi Inaba1.   

Abstract

In this paper we consider an age-duration-structured population model for HIV infection in a homosexual community. First we investigate the invasion problem to establish the basic reproduction ratio R(0) for the HIV/AIDS epidemic by which we can state the threshold criteria: The disease can invade into the completely susceptible population if R(0)>1, whereas it cannot if R(0)<1. Subsequently, we examine existence and uniqueness of endemic steady states. We will show sufficient conditions for a backward or a forward bifurcation to occur when the basic reproduction ratio crosses unity. That is, in contrast with classical epidemic models, for our HIV model there could exist multiple endemic steady states even if R(0) is less than one. Finally, we show sufficient conditions for the local stability of the endemic steady states.

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Year:  2006        PMID: 16466752     DOI: 10.1016/j.mbs.2005.12.017

Source DB:  PubMed          Journal:  Math Biosci        ISSN: 0025-5564            Impact factor:   2.144


  2 in total

Review 1.  Mathematical models for the study of HIV spread and control amongst men who have sex with men.

Authors:  Narat Punyacharoensin; William John Edmunds; Daniela De Angelis; Richard Guy White
Journal:  Eur J Epidemiol       Date:  2011-09-20       Impact factor: 8.082

2.  Generality of endemic prevalence formulae.

Authors:  Damian Clancy
Journal:  Math Biosci       Date:  2015-08-29       Impact factor: 2.144

  2 in total

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