| Literature DB >> 16466751 |
Liancheng Wang1, Michael Y Li.
Abstract
A mathematical model that describes HIV infection of CD4(+) T cells is analyzed. Global dynamics of the model is rigorously established. We prove that, if the basic reproduction number R(0) < or = 1, the HIV infection is cleared from the T-cell population; if R(0) > 1, the HIV infection persists. For an open set of parameter values, the chronic-infection equilibrium P* can be unstable and periodic solutions may exist. We establish parameter regions for which P* is globally stable.Entities:
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Year: 2006 PMID： 16466751 DOI： 10.1016/j.mbs.2005.12.026
Source DB: PubMed Journal: Math Biosci ISSN： 0025-5564 Impact factor: 2.144