Literature DB >> 16465345

Organocatalytic C3-selective Friedel-Crafts alkylations of indoles with alpha,beta-unsaturated ketones.

Dong-Ping Li1, Ying-Cen Guo, Yu Ding, Wen-Jing Xiao.   

Abstract

The use of an equimolar amount of pyrrolidine and HClO4 (30 mol%) was found to be effective in promoting the conjugate addition of indoles to (E)-alpha,beta-unsaturated ketones, affording the corresponding beta-indolyl ketones in excellent yields.

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Year:  2006        PMID： 16465345     DOI： 10.1039/b514648h

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  2 in total

1.  Catalytic asymmetric total syntheses of myrtucommuacetalone, myrtucommuacetalone B, and callistrilones A, C, D and E.

Authors:  Min-Jing Cheng; Jia-Qing Cao; Xin-Yi Yang; Li-Ping Zhong; Li-Jun Hu; Xi Lu; Bao-Long Hou; Ya-Jian Hu; Ying Wang; Xue-Fu You; Lei Wang; Wen-Cai Ye; Chuang-Chuang Li
Journal:  Chem Sci       Date:  2017-11-27       Impact factor: 9.825

2.  An efficient synthesis of 1-aryl-3-(indole-3-yl)-3-(2-aryl-1,2,3-triazol-4-yl)propan-1-one catalyzed by a Brønsted acid ionic liquid.

Authors:  Chen-Jiang Liu; Chuan-Ji Yu
Journal:  Molecules       Date:  2010-12-10       Impact factor: 4.411
  2 in total

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