Literature DB >> 16464962

Randomised controlled trial of combined paracetamol and ibuprofen for fever.

M D S Erlewyn-Lajeunesse1, K Coppens, L P Hunt, P J Chinnick, P Davies, I M Higginson, J R Benger.   

Abstract

A randomised open label study of the combined use of paracetamol and ibuprofen to rapidly reduce fever is reported. The advantage of using both medications is less than half a degree centigrade in the first hour, and insufficient to warrant routine use.

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Year:  2006        PMID： 16464962      PMCID： PMC2082718          DOI： 10.1136/adc.2005.087874

Source DB:  PubMed          Journal:  Arch Dis Child        ISSN： 0003-9888            Impact factor:   3.791


  5 in total

1.  Ibuprofen and acute renal failure in a toddler.

Authors:  N E Moghal; S Hegde; K M Eastham
Journal:  Arch Dis Child       Date:  2004-03       Impact factor: 3.791

2.  Hypothermia following fever.

Authors:  J Richardson; J Sills
Journal:  Arch Dis Child       Date:  2004-12       Impact factor: 3.791

3.  Alternating antipyretics: is this an alternative?

Authors:  C E Mayoral; R V Marino; W Rosenfeld; J Greensher
Journal:  Pediatrics       Date:  2000-05       Impact factor: 7.124

Review 4.  Efficacy and safety of acetaminophen vs ibuprofen for treating children's pain or fever: a meta-analysis.

Authors:  David A Perrott; Tiina Piira; Belinda Goodenough; G David Champion
Journal:  Arch Pediatr Adolesc Med       Date:  2004-06

5.  Effect of acetaminophen and of low intermittent doses of diazepam on prevention of recurrences of febrile seizures.

Authors:  M Uhari; H Rantala; L Vainionpää; R Kurttila
Journal:  J Pediatr       Date:  1995-06       Impact factor: 4.406
  5 in total
  14 in total

1.  Alternating acetaminophen and ibuprofen.

Authors:  Lindsay Shortridge; Venita Harris
Journal:  Paediatr Child Health       Date:  2007-02       Impact factor: 2.253

2.  Efficacy of standard doses of Ibuprofen alone, alternating, and combined with acetaminophen for the treatment of febrile children.

Authors:  Ian M Paul; Sarah A Sturgis; Chengwu Yang; Linda Engle; Heidi Watts; Cheston M Berlin
Journal:  Clin Ther       Date:  2010-12       Impact factor: 3.393

3.  An overview of clinical pharmacology of Ibuprofen.

Authors:  Rabia Bushra; Nousheen Aslam
Journal:  Oman Med J       Date:  2010-07

4.  A prospective randomized study to evaluate the antipyretic effect of the combination of acetaminophen and ibuprofen in neurological ICU patients.

Authors:  Michael E Mullins; Matthew Empey; David Jaramillo; Sameta Sosa; Theresa Human; Michael N Diringer
Journal:  Neurocrit Care       Date:  2011-12       Impact factor: 3.210

5.  Antipyretic drugs for children.

Authors:  Alastair D Hay; Niamh Redmond; Margaret Fletcher
Journal:  BMJ       Date:  2006-07-01

6.  Comparative Analysis of Single and Combined Antipyretics Using Patient-Generated Health Data: Retrospective Observational Study.

Authors:  Yu Rang Park; Hyery Kim; Ji Ae Park; Sang Hyun Ahn; Seyun Chang; Jae Won Shin; Myeongchan Kim; Jae-Ho Lee
Journal:  JMIR Mhealth Uhealth       Date:  2021-05-26       Impact factor: 4.773

7.  Paracetamol plus ibuprofen for the treatment of fever in children (PITCH): randomised controlled trial.

Authors:  Alastair D Hay; Céire Costelloe; Niamh M Redmond; Alan A Montgomery; Margaret Fletcher; Sandra Hollinghurst; Tim J Peters
Journal:  BMJ       Date:  2008-09-02

8.  Randomized comparative trial of efficacy of paracetamol, ibuprofen and paracetamol-ibuprofen combination for treatment of febrile children.

Authors:  Falgun Indravadan Vyas; Devang Ashwinkumar Rana; Piyush M Patel; Varsha Jitendra Patel; Rekha H Bhavsar
Journal:  Perspect Clin Res       Date:  2014-01

9.  Analgesic antipyretic use among young children in the TEDDY study: no association with islet autoimmunity.

Authors:  Markus Lundgren; Leigh Johnson Steed; Roy Tamura; Berglind Jonsdottir; Patricia Gesualdo; Claire Crouch; Maija Sjöberg; Gertie Hansson; William A Hagopian; Anette G Ziegler; Marian J Rewers; Åke Lernmark; Jorma Toppari; Jin-Xiong She; Beena Akolkar; Jeffrey P Krischer; Michael J Haller; Helena Elding Larsson
Journal:  BMC Pediatr       Date:  2017-05-16       Impact factor: 2.125

10.  Comparison of Acetaminophen (Paracetamol) With Ibuprofen for Treatment of Fever or Pain in Children Younger Than 2 Years: A Systematic Review and Meta-analysis.

Authors:  Eunicia Tan; Irene Braithwaite; Christopher J D McKinlay; Stuart R Dalziel
Journal:  JAMA Netw Open       Date:  2020-10-01
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