Literature DB >> 16464597

New sesquiterpene from Vietnamese agarwood and its induction effect on brain-derived neurotrophic factor mRNA expression in vitro.

Jun-ya Ueda1, Lisa Imamura, Yasuhiro Tezuka, Quan L Tran, Masaaki Tsuda, Shigetoshi Kadota.   

Abstract

Agarwood, one of the valuable non-timber products in tropical forest, is a fragrant wood, whose ethereal fragrance has been prized in Asia for incense in ceremony, as well as sedatives in traditional medicine. We separated the 70% EtOH extract of Vietnamese agarwood, which showed significant induction effect on brain-derived neurotrophic factor (BDNF) mRNA expression in rat cultured neuronal cells, to isolate a new compound and a 2-(2-phenylethyl)chromone derivative. The new compound was determined to be a spirovetivane-type sesquiterpene, (4R,5R,7R)-1(10)-spirovetiven-11-ol-2-one, by spectroscopic data and showed induction effect of BDNF mRNA.

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Year:  2006        PMID: 16464597     DOI: 10.1016/j.bmc.2006.01.023

Source DB:  PubMed          Journal:  Bioorg Med Chem        ISSN: 0968-0896            Impact factor:   3.641


  11 in total

1.  Methyl jasmonate-induced enhancement of expression activity of Am-FaPS-1, a putative farnesyl diphosphate synthase gene from Aquilaria microcarpa.

Authors:  Yoshihide Kenmotsu; Shinjiro Ogita; Yasuo Katoh; Yoshimi Yamamura; Yasumasa Takao; Yoshiaki Tatsuo; Hiroharu Fujino; Shigetoshi Kadota; Fumiya Kurosaki
Journal:  J Nat Med       Date:  2010-08-05       Impact factor: 2.343

Review 2.  Agarwood-The Fragrant Molecules of a Wounded Tree.

Authors:  Pooja Shivanand; Nurul Fadhila Arbie; Sarayu Krishnamoorthy; Norhayati Ahmad
Journal:  Molecules       Date:  2022-05-24       Impact factor: 4.927

3.  The effect of red light and far-red light conditions on secondary metabolism in agarwood.

Authors:  Tony Chien-Yen Kuo; Chuan-Hung Chen; Shu-Hwa Chen; I-Hsuan Lu; Mei-Ju Chu; Li-Chun Huang; Chung-Yen Lin; Chien-Yu Chen; Hsiao-Feng Lo; Shih-Tong Jeng; Long-Fang O Chen
Journal:  BMC Plant Biol       Date:  2015-06-12       Impact factor: 4.215

4.  Measuring Agarwood Formation Ratio Quantitatively by Fluorescence Spectral Imaging Technique.

Authors:  Botao Huang; Duykien Nguyen; Tianyi Liu; Kaibin Jiang; Jinfen Tan; Chunxin Liu; Jing Zhao; Shaowei Huang
Journal:  Evid Based Complement Alternat Med       Date:  2015-05-18       Impact factor: 2.629

5.  Hepatoprotective potential of ethanolic extract of Aquilaria agallocha leaves against paracetamol induced hepatotoxicity in SD rats.

Authors:  Janey Alam; Md Mujahid; Yasmeen Jahan; Paramdeep Bagga; Md Azizur Rahman
Journal:  J Tradit Complement Med       Date:  2016-02-03

Review 6.  Review: Secondary Metabolites of Aquilaria, a Thymelaeaceae Genus.

Authors:  Alfinda Novi Kristanti; Mulyadi Tanjung; Nanik Siti Aminah
Journal:  Mini Rev Org Chem       Date:  2018-02       Impact factor: 2.495

7.  Agarwood Essential Oil Ameliorates Restrain Stress-Induced Anxiety and Depression by Inhibiting HPA Axis Hyperactivity.

Authors:  Shuai Wang; Canhong Wang; Zhangxin Yu; Chongming Wu; Deqian Peng; Xinmin Liu; Yangyang Liu; Yun Yang; Peng Guo; Jianhe Wei
Journal:  Int J Mol Sci       Date:  2018-11-05       Impact factor: 5.923

Review 8.  Overview of sesquiterpenes and chromones of agarwood originating from four main species of the genus Aquilaria.

Authors:  Mei Gao; Xiaomin Han; Ying Sun; Hongjiang Chen; Yun Yang; Yangyang Liu; Hui Meng; Zhihui Gao; Yanhong Xu; Zheng Zhang; Jianping Han
Journal:  RSC Adv       Date:  2019-01-30       Impact factor: 4.036

9.  Anti-inflammatory components from the root of Solanum erianthum.

Authors:  Yu-Chang Chen; Hong-Zin Lee; Hsin-Chun Chen; Chi-Luan Wen; Yueh-Hsiung Kuo; Guei-Jane Wang
Journal:  Int J Mol Sci       Date:  2013-06-14       Impact factor: 5.923

10.  Identification of cucurbitacins and assembly of a draft genome for Aquilaria agallocha.

Authors:  Chuan-Hung Chen; Tony Chien-Yen Kuo; Meng-Han Yang; Ting-Ying Chien; Mei-Ju Chu; Li-Chun Huang; Chien-Yu Chen; Hsiao-Feng Lo; Shih-Tong Jeng; Long-Fang O Chen
Journal:  BMC Genomics       Date:  2014-07-09       Impact factor: 3.969

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