Literature DB >> 16464583

N-thiolated 2-oxazolidinones: a new family of antibacterial agents for methicillin-resistant Staphylococcus aureus and Bacillus anthracis.

Rajesh Kumar Mishra1, Kevin D Revell, Cristina M Coates, Edward Turos, Sonja Dickey, Daniel V Lim.   

Abstract

In this report, we describe a new family of N-thiolated 2-oxazolidinones having antibacterial activity against methicillin-resistant Staphylococcus aureus and Bacillus anthracis. The effect of ring substituents and stereochemistry on antibacterial activity of these oxazolidinones closely parallels that previously reported for N-thiolated beta-lactam antibiotics.

Entities:  

Mesh：

Substances：

Year:  2006        PMID： 16464583     DOI： 10.1016/j.bmcl.2006.01.058

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  3 in total

1.  N-thiolated beta-lactams: Studies on the mode of action and identification of a primary cellular target in Staphylococcus aureus.

Authors:  Kevin D Revell; Bart Heldreth; Timothy E Long; Seyoung Jang; Edward Turos
Journal:  Bioorg Med Chem       Date:  2006-12-20       Impact factor: 3.641

2.  Unsymmetric aryl-alkyl disulfide growth inhibitors of methicillin-resistant Staphylococcus aureus and Bacillus anthracis.

Authors:  Edward Turos; Kevin D Revell; Praveen Ramaraju; Danielle A Gergeres; Kerriann Greenhalgh; Ashley Young; Nalini Sathyanarayan; Sonja Dickey; Daniel Lim; Mamoun M Alhamadsheh; Kevin Reynolds
Journal:  Bioorg Med Chem       Date:  2008-05-17       Impact factor: 3.641

3.  Proline-based phosphoramidite reagents for the reductive ligation of S-nitrosothiols.

Authors:  Chung-Min Park; Tyler D Biggs; Ming Xian
Journal:  J Antibiot (Tokyo)       Date:  2016-01-13       Impact factor: 2.649
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.