Literature DB >> 16462141

Sunflower seed oil-enriched product can inhibit Ehrlich solid tumor growth in mice.

Lucilene A Silva1, Kátia A F Nascimento, Márcia C G Maciel, Mayara T Pinheiro, Paulo R A Sousa, Susanne C P Ferreira, Ana Paula S Azevedo, Rosane N M Guerra, Flávia R F Nascimento.   

Abstract

BACKGROUND: Sunflower seed oil (SSO) effect on solid and ascitic forms of Ehrlich tumor was evaluated.
METHODS: Solid or ascitic Ehrlich tumor-bearing Swiss mice were treated daily, by subcutaneous route, with 200 microl of SSO. The solid tumor-bearing footpad was measured every 3 days and ascitic tumor-bearing mice had their ascites collected and quantified. At the end of the SSO treatment, the total cell number in lymphoid organs was quantified.
RESULTS: Subcutaneous treatment with SSO inhibits the solid tumor growth and increases lymph node cell number in animals with solid tumor, but has no effect on animals with ascitic tumor.
CONCLUSIONS: SSO can delay the solid tumor growth, possibly due to better absorption of this treatment by draining lymph nodes. Copyright 2006 S. Karger AG, Basel.

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Year:  2006        PMID: 16462141     DOI: 10.1159/000091308

Source DB:  PubMed          Journal:  Chemotherapy        ISSN: 0009-3157            Impact factor:   2.544


  3 in total

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  3 in total

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