| Literature DB >> 16462000 |
Yokananth Sekar1, Tae Chul Moon, Samira Muñoz, A Dean Befus.
Abstract
Mast cells (MC) are important effector cells in allergic disorders. Recently, the role of MC in innate and adaptive immunity is gaining prominence. Nitric oxide is an important signaling molecule and its production in mast cell has been reported widely. However, controversy exists about whether MC produce NO. This review addresses the role of NO in MC biology and the reasons behind the controversy and discusses effects of NO in regulation of MC phenotype and function.Entities:
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Year: 2005 PMID: 16462000 DOI: 10.1385/IR:33:3:223
Source DB: PubMed Journal: Immunol Res ISSN: 0257-277X Impact factor: 2.829