| Literature DB >> 16461319 |
Malin Ageberg, Urban Gullberg, Anders Lindmark.
Abstract
The role of the DEK protein, involved in the leukemia-associated fusion protein DEK-CAN, is not yet known. In this study, we show a higher expression of DEK mRNA in immature cells than in mature cells. Furthermore, a correlation between DEK expression and cell proliferation was demonstrated, suggesting that DEK plays a role in the proliferation of hematopoietic cells and raising the question of whether the DEK-CAN fusion protein might perturb regulation of proliferation in leukemic cells.Entities:
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Year: 2006 PMID： 16461319
Source DB: PubMed Journal: Haematologica ISSN： 0390-6078 Impact factor: 9.941