Literature DB >> 16461223

Immune system and hepatitis B virus infection.

Chee-Kin Hui1, George K K Lau.   

Abstract

The immune system plays an important role in determining the outcome of hepatitis B virus (HBV) infection. This is because recovery from of acute HBV infection is associated with a clear division in the profile of adaptive immune response. Multispecific antiviral CD4 and CD8 responses with a type 1 cytokine production can be observed in patients who recover from acute HBV infection. On the other hand, those who develop chronic infection tend to have a weak virus specific T cell response. Therapeutic strategies aimed at correcting this defective T cell reactivity could represent a complementary approach to the cure of chronic HBV infection.

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Year:  2005        PMID: 16461223     DOI: 10.1016/s1386-6532(05)80009-5

Source DB:  PubMed          Journal:  J Clin Virol        ISSN: 1386-6532            Impact factor:   3.168


  17 in total

1.  Cell-type-specific tyrosine phosphorylation of the herpes simplex virus tegument protein VP11/12 encoded by gene UL46.

Authors:  George Zahariadis; Melany J Wagner; Rosalyn C Doepker; Jessica M Maciejko; Carly M Crider; Keith R Jerome; James R Smiley
Journal:  J Virol       Date:  2008-04-16       Impact factor: 5.103

2.  A disparate subset of double-negative T cells contributes to the outcome of murine fulminant viral hepatitis via effector molecule fibrinogen-like protein 2.

Authors:  Di Wu; Hongwu Wang; Weiming Yan; Tao Chen; Ming Wang; Meifang Han; Zeguang Wu; Xiaojing Wang; Guo Ai; Dong Xi; Guanxin Shen; Xiaoping Luo; Qin Ning
Journal:  Immunol Res       Date:  2016-04       Impact factor: 2.829

3.  γδ T Cells Contribute to the Outcome of Murine Fulminant Viral Hepatitis via Effector Cytokines TNF-α and IFN-γ.

Authors:  Di Wu; Wei-Ming Yan; Hong-Wu Wang; Da Huang; Xiao-Ping Luo; Qin Ning
Journal:  Curr Med Sci       Date:  2018-08-20

4.  Association between interferon-gamma (IFN-γ) gene polymorphisms (+874A/T and +2109A/G), and susceptibility to hepatitis B viral infection (HBV).

Authors:  Mahmoud F Dondeti; Mohamed S Abdelkhalek; Hosam M El-Din Elezawy; Walaa F Alsanie; Bassem M Raafat; Amira M Gamal-Eldeen; Roba M Talaat
Journal:  J Appl Biomed       Date:  2022-01-12       Impact factor: 1.797

Review 5.  Hepatitis-related hepatocellular carcinoma: Insights into cytokine gene polymorphisms.

Authors:  Mahmoud Fathy Dondeti; Eman Anwar El-Maadawy; Roba Mohamed Talaat
Journal:  World J Gastroenterol       Date:  2016-08-14       Impact factor: 5.742

6.  Toll-like receptor 2 promotes T helper 17 cells response in hepatitis B virus infection.

Authors:  Rong-Rong Zhao; Xiao-Fei Yang; Jie Dong; Yan-Yan Zhao; Xin Wei; Chang-Xing Huang; Jian-Qi Lian; Ye Zhang
Journal:  Int J Clin Exp Med       Date:  2015-05-15

7.  Evaluation of Interleukin-10 Levels in Patients Diagnosed with Chronic Hepatitis.

Authors:  M Özgüler; H H Akbulut; A Akbulut
Journal:  West Indian Med J       Date:  2015-01-27       Impact factor: 0.171

8.  Enchanced levels of apolipoprotein M during HBV infection feedback suppresses HBV replication.

Authors:  Jin-Gang Gu; Cheng-liang Zhu; Duo-zhi Cheng; Yan Xie; Fang Liu; Xin Zhou
Journal:  Lipids Health Dis       Date:  2011-08-29       Impact factor: 3.876

9.  Association between the frequency of class II HLA antigens and the susceptibility to intrauterine infection of hepatitis B virus.

Authors:  Yuan-yong Xu; Ji-yun Yu; Yan-wei Zhong; Hong-bin Song; Hui-hui Liu; Lei-li Jia; Shen-long Li; Jian-qiu Xu; Qiao Li
Journal:  Int J Biol Sci       Date:  2008-04-25       Impact factor: 6.580

10.  miR-106a Is Downregulated in Peripheral Blood Mononuclear Cells of Chronic Hepatitis B and Associated with Enhanced Levels of Interleukin-8.

Authors:  Zhongsi Hong; Haiyu Hong; Jian Liu; Xiaobin Zheng; Mingxing Huang; Chunna Li; Jinyu Xia
Journal:  Mediators Inflamm       Date:  2015-07-22       Impact factor: 4.711

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