| Literature DB >> 16461223 |
Chee-Kin Hui1, George K K Lau.
Abstract
The immune system plays an important role in determining the outcome of hepatitis B virus (HBV) infection. This is because recovery from of acute HBV infection is associated with a clear division in the profile of adaptive immune response. Multispecific antiviral CD4 and CD8 responses with a type 1 cytokine production can be observed in patients who recover from acute HBV infection. On the other hand, those who develop chronic infection tend to have a weak virus specific T cell response. Therapeutic strategies aimed at correcting this defective T cell reactivity could represent a complementary approach to the cure of chronic HBV infection.Entities:
Mesh:
Year: 2005 PMID: 16461223 DOI: 10.1016/s1386-6532(05)80009-5
Source DB: PubMed Journal: J Clin Virol ISSN: 1386-6532 Impact factor: 3.168