Literature DB >> 16461203

An updated meta-analysis of genome scans for hypertension and blood pressure in the NHLBI Family Blood Pressure Program (FBPP).

Xiaodong Wu1, Donghui Kan, Michael Province, Tom Quertermous, D C Rao, Christy Chang, Thomas H Mosley, David Curb, Eric Boerwinkle, Richard S Cooper.   

Abstract

A meta-analysis of the results from a multicenter genome-wide linkage study for hypertension and blood pressure (BP) based on an initial sample of 6,245 individuals was published in 2003. We report here a combined linkage analysis of hypertension and BP using the complete Family Blood Pressure Program (FBPP) dataset, which includes a total of 12,028 genotyped individuals. Genome-wide linkage analyses for hypertension and BP were first performed in each of the studied ethnic group within each network and the results were combined with a meta-analysis using a modified Fisher's method of combining P values. Our meta-analysis of genome scans for the latest FBPP dataset reveals suggestive linkage for hypertension and BP at several regions on the human genome. Strong evidence for linkage at two of these regions, 2p14 and 3p14.1, have also been published in previous meta-analyses, making them good candidate locations for susceptibility variants.

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Year:  2006        PMID： 16461203     DOI： 10.1016/j.amjhyper.2005.07.010

Source DB:  PubMed          Journal:  Am J Hypertens        ISSN： 0895-7061            Impact factor:   2.689


  12 in total

1.  Combined linkage and association analysis identifies rare and low frequency variants for blood pressure at 1q31.

Authors:  Heming Wang; Priyanka Nandakumar; Fasil Tekola-Ayele; Bamidele O Tayo; Erin B Ware; C Charles Gu; Yingchang Lu; Jie Yao; Wei Zhao; Jennifer A Smith; Jacklyn N Hellwege; Xiuqing Guo; Todd L Edwards; Ruth J F Loos; Donna K Arnett; Myriam Fornage; Charles Rotimi; Sharon L R Kardia; Richard S Cooper; D C Rao; Georg Ehret; Aravinda Chakravarti; Xiaofeng Zhu
Journal:  Eur J Hum Genet       Date:  2018-09-27       Impact factor: 4.246

2.  Are "functionally related polymorphisms" of renin-angiotensin-aldosterone system gene polymorphisms associated with hypertension?

Authors:  Ines N Hahntow; Gideon Mairuhu; Irene Gm van Valkengoed; Richard P Koopmans; Martin C Michel
Journal:  BMC Cardiovasc Disord       Date:  2010-06-02       Impact factor: 2.298

3.  Interactions between obesity, parental history of hypertension, and age on prevalent hypertension: the People's Republic of China Study.

Authors:  Eva G Katz; June Stevens; Kimberly P Truesdale; Jianwen Cai; Kari E North
Journal:  Asia Pac J Public Health       Date:  2011-06-08       Impact factor: 1.399

4.  Five blood pressure loci identified by an updated genome-wide linkage scan: meta-analysis of the Family Blood Pressure Program.

Authors:  Jeannette Simino; Gang Shi; Rezart Kume; Karen Schwander; Michael A Province; C Charles Gu; Sharon Kardia; Aravinda Chakravarti; Georg Ehret; Richard A Olshen; Stephen T Turner; Low-Tone Ho; Xiaofeng Zhu; Cashell Jaquish; Dina Paltoo; Richard S Cooper; Alan Weder; J David Curb; Eric Boerwinkle; Steven C Hunt; Dabeeru C Rao
Journal:  Am J Hypertens       Date:  2010-12-09       Impact factor: 2.689

5.  Genome-wide association study of young-onset hypertension in the Han Chinese population of Taiwan.

Authors:  Hsin-Chou Yang; Yu-Jen Liang; Yi-Lin Wu; Chia-Min Chung; Kuang-Mao Chiang; Hung-Yun Ho; Chih-Tai Ting; Tsung-Hsien Lin; Sheng-Hsiung Sheu; Wei-Chuan Tsai; Jyh-Hong Chen; Hsin-Bang Leu; Wei-Hsian Yin; Ting-Yu Chiu; Chin-Iuan Chen; Cathy S J Fann; Jer-Yuarn Wu; Teng-Nan Lin; Shing-Jong Lin; Yuan-Tsong Chen; Jaw-Wen Chen; Wen-Harn Pan
Journal:  PLoS One       Date:  2009-05-07       Impact factor: 3.240

Review 6.  Angiotensin II type 1 receptor polymorphisms and susceptibility to hypertension: a HuGE review.

Authors:  Amy K Mottl; David A Shoham; Kari E North
Journal:  Genet Med       Date:  2008-08       Impact factor: 8.822

7.  Gene by smoking interaction in hypertension: identification of a major quantitative trait locus on chromosome 15q for systolic blood pressure in Mexican-Americans.

Authors:  May E Montasser; Lawrence C Shimmin; Craig L Hanis; Eric Boerwinkle; James E Hixson
Journal:  J Hypertens       Date:  2009-03       Impact factor: 4.844

8.  Angiotensin II type 1 receptor A1166C gene polymorphism and essential hypertension in Calabar and Uyo cities, Nigeria.

Authors:  Mary Esien Kooffreh; Chiaka Ijeoma Anumudu; Roseline Duke; Elza Cletus Okpako; P Lava Kumar
Journal:  Indian J Hum Genet       Date:  2013-04

9.  Rare variants in fox-1 homolog A (RBFOX1) are associated with lower blood pressure.

Authors:  Karen Y He; Heming Wang; Brian E Cade; Priyanka Nandakumar; Ayush Giri; Erin B Ware; Jeffrey Haessler; Jingjing Liang; Jennifer A Smith; Nora Franceschini; Thu H Le; Charles Kooperberg; Todd L Edwards; Sharon L R Kardia; Xihong Lin; Aravinda Chakravarti; Susan Redline; Xiaofeng Zhu
Journal:  PLoS Genet       Date:  2017-03-27       Impact factor: 5.917

10.  A high-density admixture scan in 1,670 African Americans with hypertension.

Authors:  Rahul C Deo; Nick Patterson; Arti Tandon; Gavin J McDonald; Christopher A Haiman; Kristin Ardlie; Brian E Henderson; Sean O Henderson; David Reich
Journal:  PLoS Genet       Date:  2007-11       Impact factor: 5.917
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