Eric W Sellers1, Emanuel Donchin. 1. New York State Department of Health, Wadsworth Center, E1001 Empire State Plaza, Albany, NY 12201, USA. esellers@wadsworth.org
Abstract
OBJECTIVE: The current study evaluates the effectiveness of a brain-computer interface (BCI) system that operates by detecting a P300 elicited by one of four randomly presented stimuli (i.e. YES, NO, PASS, END). METHODS: Two groups of participants were tested. The first group included three amyotrophic lateral sclerosis (ALS) patients that varied in degree of disability, but all retained the ability to communicate; the second group included three non-ALS controls. Each participant participated in ten experimental sessions during a period of approximately 6 weeks. During each run the participant's task was to attend to one stimulus and disregard the other three. Stimuli were presented auditorily, visually, or in both modes. RESULTS: Two of the 3 ALS patient's classification rates were equal to those achieved by the non-ALS participants. Waveform morphology varied as a function of the presentation mode, but not in a similar pattern for each participant. CONCLUSIONS: The event-related potentials elicited by the target stimuli could be discriminated from the non-target stimuli for the non-ALS and the ALS groups. Future studies will begin to examine online classification. SIGNIFICANCE: The results of offline classification suggest that a P300-based BCI can serve as a non-muscular communication device in both ALS, and non-ALS control groups.
OBJECTIVE: The current study evaluates the effectiveness of a brain-computer interface (BCI) system that operates by detecting a P300 elicited by one of four randomly presented stimuli (i.e. YES, NO, PASS, END). METHODS: Two groups of participants were tested. The first group included three amyotrophic lateral sclerosis (ALS) patients that varied in degree of disability, but all retained the ability to communicate; the second group included three non-ALS controls. Each participant participated in ten experimental sessions during a period of approximately 6 weeks. During each run the participant's task was to attend to one stimulus and disregard the other three. Stimuli were presented auditorily, visually, or in both modes. RESULTS: Two of the 3 ALS patient's classification rates were equal to those achieved by the non-ALS participants. Waveform morphology varied as a function of the presentation mode, but not in a similar pattern for each participant. CONCLUSIONS: The event-related potentials elicited by the target stimuli could be discriminated from the non-target stimuli for the non-ALS and the ALS groups. Future studies will begin to examine online classification. SIGNIFICANCE: The results of offline classification suggest that a P300-based BCI can serve as a non-muscular communication device in both ALS, and non-ALS control groups.
Authors: D B Ryan; G E Frye; G Townsend; D R Berry; S Mesa-G; N A Gates; E W Sellers Journal: Int J Hum Comput Interact Date: 2011-01-01 Impact factor: 3.353
Authors: G Townsend; B K LaPallo; C B Boulay; D J Krusienski; G E Frye; C K Hauser; N E Schwartz; T M Vaughan; J R Wolpaw; E W Sellers Journal: Clin Neurophysiol Date: 2010-03-26 Impact factor: 3.708
Authors: Lynn M McCane; Eric W Sellers; Dennis J McFarland; Joseph N Mak; C Steve Carmack; Debra Zeitlin; Jonathan R Wolpaw; Theresa M Vaughan Journal: Amyotroph Lateral Scler Frontotemporal Degener Date: 2014-02-20 Impact factor: 4.092
Authors: Wei Wang; Jennifer L Collinger; Monica A Perez; Elizabeth C Tyler-Kabara; Leonardo G Cohen; Niels Birbaumer; Steven W Brose; Andrew B Schwartz; Michael L Boninger; Douglas J Weber Journal: Phys Med Rehabil Clin N Am Date: 2010-02 Impact factor: 1.784