Literature DB >> 16460951

Study on the compounds containing 19F and 10B atoms in a single molecule for the application to MRI and BNCT.

Yoshihide Hattori1, Tomoyuki Asano, Yoko Niki, Hirofumi Kondoh, Mitsunori Kirihata, Yoshihiro Yamaguchi, Tateaki Wakamiya.   

Abstract

Magnetic resonance imaging (MRI) and boron-neutron capture therapy (BNCT) are quite attractive techniques for diagnosis and treatment of cancer, respectively. In order to progress the study on both MRI and BNCT, the novel compounds containing 19F and 10B atoms in a single molecule were designed and synthesized. In the present paper, the syntheses and the internalization rates into tumor cells of these compounds are elucidated.

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Year:  2006        PMID: 16460951     DOI: 10.1016/j.bmc.2005.10.062

Source DB:  PubMed          Journal:  Bioorg Med Chem        ISSN: 0968-0896            Impact factor:   3.641


  2 in total

1.  Boron Accumulation in Brain Tumor Cells through Boc-Protected Tryptophan as a Carrier for Boron Neutron Capture Therapy.

Authors:  Chun-Ming Chio; Ying-Cheng Huang; You-Cheng Chou; Fu-Chun Hsu; Yen-Buo Lai; Chung-Shan Yu
Journal:  ACS Med Chem Lett       Date:  2020-03-16       Impact factor: 4.345

2.  Therapeutic potential of atmospheric neutrons.

Authors:  Cyril Voyant; Rudy Roustit; Jennifer Tatje; Katia Biffi; Delphine Leschi; Jérome Briançon; Céline Lantieri Marcovici
Journal:  Rep Pract Oncol Radiother       Date:  2010-12-04
  2 in total

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