| Literature DB >> 16460065 |
Massimo Bonini1, Simona Rossi, Göran Karlsson, Mats Almgren, Pierandrea Lo Nostro, Piero Baglioni.
Abstract
In this article, we report evidence of beta-cyclodextrin (beta-CD) self-aggregation in water. A critical aggregation concentration (cac) between 2 and 3 mM was determined by using dynamic (DLS) and static (SLS) light scattering to investigate the presence of beta-cyclodextrin aggregates. Transmission electron microscopy at cryogenic temperature (Cryo-TEM) was used to detect the structural features of cyclodextrin self-aggregates. The results show the occurrence of polymorphism depending on the beta-CD concentration: polydisperse nearly spherical objects with diameters of about 100 nm are present at lower concentrations, whereas micrometer planar aggregates are predominant at higher concentrations.Entities:
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Year: 2006 PMID： 16460065 DOI： 10.1021/la052878f
Source DB: PubMed Journal: Langmuir ISSN： 0743-7463 Impact factor: 3.882