Literature DB >> 1645953

Gene expression of fibroblast growth factor receptors in the tissues of human gliomas and meningiomas.

J A Takahashi1, H Suzui, Y Yasuda, N Ito, M Ohta, M Jaye, M Fukumoto, Y Oda, H Kikuchi, M Hatanaka.   

Abstract

Northern blot analysis showed transcripts of two types of the fibroblast growth factor (FGF) receptor genes, flg and bek, in almost all the tissues samples of 18 human gliomas and 22 human meningiomas, which produced abundant basic and/or acidic FGF. From immunohistochemistry, FGF receptors were expressed in the tumor cells of a glioma and a meningioma. RNA expression of these FGF receptors was also detectable in normal human brains and normal bovine meninges. The expression level of either FGF receptor gene was not significantly different between tumor tissues and normal tissues.

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Year:  1991        PMID： 1645953     DOI： 10.1016/0006-291x(91)91939-a

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  9 in total

Review 1.  Angiogenic growth factors in neural embryogenesis and neoplasia.

Authors:  D Zagzag
Journal:  Am J Pathol       Date:  1995-02       Impact factor: 4.307

Review 2.  Aberrant signaling pathways in meningiomas.

Authors:  Brian T Ragel; Randy L Jensen
Journal:  J Neurooncol       Date:  2010-09-14       Impact factor: 4.130

Review 3.  Growth factor regulation of cell growth and proliferation in the nervous system. A new intracrine nuclear mechanism.

Authors:  M K Stachowiak; J Moffett; P Maher; J Tucholski; E K Stachowiak
Journal:  Mol Neurobiol       Date:  1997-12       Impact factor: 5.590

4.  Adenovirus-mediated gene transfer of a truncated form of fibroblast growth factor receptor inhibits growth of glioma cells both in vitro and in vivo.

Authors:  M Saiki; T Mima; J C Takahashi; S Tani; H Yukawa; H Ueno; T Mikawa; N Itoh; H Kikuchi; N Hashimoto; S Miyatake
Journal:  J Neurooncol       Date:  1999       Impact factor: 4.130

5.  Scintigraphic detection of xenografted tumors producing human basic fibroblast growth factor.

Authors:  H Kobayashi; H Sakahara; M Hosono; M Shirato; J Konishi; J A Takahashi; Y Oda; H Kikuchi; K Endo; Y Kozai
Journal:  Cancer Immunol Immunother       Date:  1993-10       Impact factor: 6.968

6.  Endothelin receptor in microvessels isolated from human meningiomas: quantification with radioluminography.

Authors:  S Yamaga; K Tsutsumi; M Niwa; N Kitagawa; T Anda; A Himeno; H Khalid; K Taniyama; S Shibata
Journal:  Cell Mol Neurobiol       Date:  1995-06       Impact factor: 5.046

7.  Transcriptional regulation of basic fibroblast growth factor gene by p53 in human glioblastoma and hepatocellular carcinoma cells.

Authors:  T Ueba; T Nosaka; J A Takahashi; F Shibata; R Z Florkiewicz; B Vogelstein; Y Oda; H Kikuchi; M Hatanaka
Journal:  Proc Natl Acad Sci U S A       Date:  1994-09-13       Impact factor: 11.205

8.  In vitro growth suppression of human glioma cells by a 16-mer oligopeptide: a potential new treatment modality for malignant glioma.

Authors:  Katsuhiko Kono; Tetsuya Ueba; Jun A Takahashi; Nozomu Murai; Nobuo Hashimoto; Akira Myoumoto; Nobuo Itoh; Manabu Fukumoto
Journal:  J Neurooncol       Date:  2003-06       Impact factor: 4.130

Review 9.  Role of YY1 in the pathogenesis of prostate cancer and correlation with bioinformatic data sets of gene expression.

Authors:  Vaishali Kashyap; Benjamin Bonavida
Journal:  Genes Cancer       Date:  2014-03
  9 in total

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