| Literature DB >> 16459291 |
Fernando Diaz1, Enrique Rodriguez-Boulan.
Abstract
In the January 13 issue of Cell, Coyne and Bergelson describe an "Open sesame!" strategy developed by coxsackieviruses to invade the organism through the intestinal epithelium. The strategy involves coopting intrinsic signaling abilities of the apical GPI-anchored protein DAF to open the tight junction barrier, gain access to the primary receptor CAR, and activate virus internalization by a caveolin-dependent pathway.Entities:
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Year: 2006 PMID： 16459291 DOI： 10.1016/j.devcel.2006.01.005
Source DB: PubMed Journal: Dev Cell ISSN： 1534-5807 Impact factor: 12.270