| Literature DB >> 16459126 |
David J Burn1, Watcharee Tiangyou, Liesl M Allcock, Jill Davison, Patrick F Chinnery.
Abstract
A genetic susceptibility to depression in PD, acting via the serotonergic system, has been suggested. We examined the influence of allelic variation (L/S) in a functional polymorphism in the serotonin transporter (5-HTTLPR) gene upon mood in 108 PD patients and 82 controls. Using a logistic regression model we found no evidence for an association between 5-HTTLPR genotypes, or the presence of the S allele, and depression.Entities:
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Year: 2006 PMID： 16459126 DOI： 10.1016/j.parkreldis.2005.11.005
Source DB: PubMed Journal: Parkinsonism Relat Disord ISSN： 1353-8020 Impact factor: 4.891