Literature DB >> 16458867

A beta-D-glucan isolated from the fruiting bodies of Hericium erinaceus and its aqueous conformation.

Qun Dong1, Lian-Meng Jia, Ji-Nian Fang.   

Abstract

HEP3, a beta-D-glucan slightly soluble in water, was isolated from the alkaline extract of the fruiting bodies of Hericium erinaceus. Its chemical structure was investigated by methylation analysis, periodate oxidation, Smith degradation and by IR and NMR spectroscopy. It was shown to have a main chain composed of beta-(1-->3)-linked D-glucopyranosyl residues, with single unit glucosyl branches attached to O-6 of every third backbone residue. Viscometry and Congo red reaction indicated that HEP3 has a highly ordered hydrogen-bond dependent conformation in aqueous solution, which collapses in strong alkaline solution.

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Year:  2006        PMID: 16458867     DOI: 10.1016/j.carres.2006.01.022

Source DB:  PubMed          Journal:  Carbohydr Res        ISSN: 0008-6215            Impact factor:   2.104


  4 in total

1.  Structure of a β-glucan from Grifola frondosa and its antitumor effect by activating Dectin-1/Syk/NF-κB signaling.

Authors:  Jianping Fang; Ying Wang; Xiaofen Lv; Xiaokun Shen; Xinyan Ni; Kan Ding
Journal:  Glycoconj J       Date:  2012-06-29       Impact factor: 2.916

2.  Src kinase-targeted anti-inflammatory activity of davallialactone from Inonotus xeranticus in lipopolysaccharide-activated RAW264.7 cells.

Authors:  Y G Lee; W M Lee; J Y Kim; J Y Lee; I-K Lee; B-S Yun; M H Rhee; J Y Cho
Journal:  Br J Pharmacol       Date:  2008-05-05       Impact factor: 8.739

3.  A RG-II type polysaccharide purified from Aconitum coreanum alleviates lipopolysaccharide-induced inflammation by inhibiting the NF-κB signal pathway.

Authors:  Xiaojun Li; Jiaye Jiang; Songshan Shi; S W Annie Bligh; Yuan Li; Yongbo Jiang; Dan Huang; Yan Ke; Shunchun Wang
Journal:  PLoS One       Date:  2014-06-13       Impact factor: 3.240

Review 4.  A Review on the Structure and Anti-Diabetic (Type 2) Functions of β-Glucans.

Authors:  Yujun Wan; Xiaojuan Xu; Robert G Gilbert; Mitchell A Sullivan
Journal:  Foods       Date:  2021-12-27
  4 in total

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