Literature DB >> 16458534

CD4+CD25+ regulatory T lymphocytes in bone marrow transplantation.

Olivier Joffre1, Joost P M van Meerwijk.   

Abstract

Induction of immunological tolerance to alloantigens would be the treatment of choice to prevent graft-versus-host disease (GvHD) and allograft rejection in transplantation medicine. Organisms use a variety of mechanisms to avoid potentially deadly immunity to self-antigens. The most potent self-tolerance mechanism is probably dominant tolerance assured by regulatory and suppressor T lymphocytes. It appears therefore attractive to use the same mechanism to induce transplantation-tolerance. We here review and discuss recent advances in the use of one of the best-characterized regulatory T lymphocyte populations, CD4(+)CD25(+) T cells, to prevent graft-versus-host disease and bone marrow allograft rejection.

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Year:  2006        PMID： 16458534      PMCID： PMC1950263          DOI： 10.1016/j.smim.2006.01.005

Source DB:  PubMed          Journal:  Semin Immunol        ISSN： 1044-5323            Impact factor:   11.130


  74 in total

1.  Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecific.

Authors:  A M Thornton; E M Shevach
Journal:  J Immunol       Date:  2000-01-01       Impact factor: 5.422

Review 2.  Regulatory T cells: key controllers of immunologic self-tolerance.

Authors:  S Sakaguchi
Journal:  Cell       Date:  2000-05-26       Impact factor: 41.582

Review 3.  Regulatory T cells in autoimmmunity*.

Authors:  E M Shevach
Journal:  Annu Rev Immunol       Date:  2000       Impact factor: 28.527

4.  Impact of negative selection on the T cell repertoire reactive to a self-peptide: a large fraction of T cell clones escapes clonal deletion.

Authors:  C Bouneaud; P Kourilsky; P Bousso
Journal:  Immunity       Date:  2000-12       Impact factor: 31.745

Review 5.  Transplantation tolerance-where do we stand?

Authors:  H Waldmann
Journal:  Nat Med       Date:  1999-11       Impact factor: 53.440

6.  The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3.

Authors:  C L Bennett; J Christie; F Ramsdell; M E Brunkow; P J Ferguson; L Whitesell; T E Kelly; F T Saulsbury; P F Chance; H D Ochs
Journal:  Nat Genet       Date:  2001-01       Impact factor: 38.330

7.  Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse.

Authors:  M E Brunkow; E W Jeffery; K A Hjerrild; B Paeper; L B Clark; S A Yasayko; J E Wilkinson; D Galas; S F Ziegler; F Ramsdell
Journal:  Nat Genet       Date:  2001-01       Impact factor: 38.330

8.  B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes.

Authors:  B Salomon; D J Lenschow; L Rhee; N Ashourian; B Singh; A Sharpe; J A Bluestone
Journal:  Immunity       Date:  2000-04       Impact factor: 31.745

9.  CD25 is a marker for CD4+ thymocytes that prevent autoimmune diabetes in rats, but peripheral T cells with this function are found in both CD25+ and CD25- subpopulations.

Authors:  L A Stephens; D Mason
Journal:  J Immunol       Date:  2000-09-15       Impact factor: 5.422

10.  An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation.

Authors:  C Asseman; S Mauze; M W Leach; R L Coffman; F Powrie
Journal:  J Exp Med       Date:  1999-10-04       Impact factor: 14.307
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  14 in total

Review 1.  Physiologic regulation of central and peripheral T cell tolerance: lessons for therapeutic applications.

Authors:  Lequn Li; Vassiliki A Boussiotis
Journal:  J Mol Med (Berl)       Date:  2006-09-14       Impact factor: 4.599

2.  An MHC-linked locus modulates thymic differentiation of CD4+CD25+Foxp3+ regulatory T lymphocytes.

Authors:  Julie Tellier; Joost P M van Meerwijk; Paola Romagnoli
Journal:  Int Immunol       Date:  2006-08-30       Impact factor: 4.823

3.  A crucial role for host APCs in the induction of donor CD4+CD25+ regulatory T cell-mediated suppression of experimental graft-versus-host disease.

Authors:  Isao Tawara; Warren D Shlomchik; Angela Jones; Weiping Zou; Evelyn Nieves; Chen Liu; Tomomi Toubai; Raimon Duran-Struuck; Yaping Sun; Shawn G Clouthier; Rebecca Evers; Kathleen P Lowler; Robert B Levy; Pavan Reddy
Journal:  J Immunol       Date:  2010-09-01       Impact factor: 5.422

4.  Shaping of the autoreactive regulatory T cell repertoire by thymic cortical positive selection.

Authors:  Julie Ribot; Geneviève Enault; Sylvie Pilipenko; Anne Huchenq; Maryline Calise; Denis Hudrisier; Paola Romagnoli; Joost P M van Meerwijk
Journal:  J Immunol       Date:  2007-11-15       Impact factor: 5.422

5.  Induction of antigen-specific regulatory T cells in wild-type mice: visualization and targets of suppression.

Authors:  Panayotis Verginis; Katherine A McLaughlin; Kai W Wucherpfennig; Harald von Boehmer; Irina Apostolou
Journal:  Proc Natl Acad Sci U S A       Date:  2008-02-25       Impact factor: 11.205

6.  In situ activation and expansion of host tregs: a new approach to enhance donor chimerism and stable engraftment in major histocompatibility complex-matched allogeneic hematopoietic cell transplantation.

Authors:  Alwi Shatry; Robert B Levy
Journal:  Biol Blood Marrow Transplant       Date:  2009-05-07       Impact factor: 5.742

7.  Prevention of acute and chronic allograft rejection with CD4+CD25+Foxp3+ regulatory T lymphocytes.

Authors:  Olivier Joffre; Thibault Santolaria; Denis Calise; Talal Al Saati; Denis Hudrisier; Paola Romagnoli; Joost P M van Meerwijk
Journal:  Nat Med       Date:  2007-12-09       Impact factor: 53.440

8.  Efficient generation of human alloantigen-specific CD4+ regulatory T cells from naive precursors by CD40-activated B cells.

Authors:  Wenwei Tu; Yu-Lung Lau; Jian Zheng; Yinping Liu; Ping-Lung Chan; Huawei Mao; Kira Dionis; Pascal Schneider; David B Lewis
Journal:  Blood       Date:  2008-07-03       Impact factor: 22.113

9.  The influence of CD4 T-cell subsets on control of CD4 T-cell-mediated graft-versus-host disease.

Authors:  Halima Moncrieffe; Mark Coles; Brigitta Stockinger
Journal:  Immunology       Date:  2008-05-20       Impact factor: 7.397

Review 10.  A novel mechanism for immunosuppression: from neuropeptides to regulatory T cells.

Authors:  Doina Ganea; Elena Gonzalez-Rey; Mario Delgado
Journal:  J Neuroimmune Pharmacol       Date:  2006-10-10       Impact factor: 4.147
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