Literature DB >> 1645668

Isolated adrenocorticotropic hormone deficiency associated with common variable immunodeficiency.

P A Tovo1, R Lala, S Martino, G Pastorelli, C De Sanctis.   

Abstract

A 14-year-old girl has been suffering from an isolated adrenocorticotropin hormone (ACTH) deficiency with secondary glucocorticoid deficiency and common variable immunodeficiency since the age of 6.6 years. Human corticotropin releasing hormone administration did not increase ACTH and cortisol levels, strongly suggesting a pituitary deficiency. Despite the profound humoral defect, severe infections have never developed and the antibody response to herpes viruses was intact. We speculate that the association between two rare disorders, simultaneously diagnosed 2 months after measles, is not coincidental but caused by close interactions between neuro-endocrine and immune systems.

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Year:  1991        PMID： 1645668     DOI： 10.1007/bf02093717

Source DB:  PubMed          Journal:  Eur J Pediatr        ISSN： 0340-6199            Impact factor:   3.183


  19 in total

1.  Isolated ACTH deficiency in childhood: lack of response to corticotropin-releasing hormone alone and in combination with arginine vasopressin.

Authors:  D E Carey
Journal:  J Pediatr       Date:  1985-12       Impact factor: 4.406

2.  Childhood common variable immunodeficiency with autoimmune disease.

Authors:  M E Conley; C L Park; S D Douglas
Journal:  J Pediatr       Date:  1986-06       Impact factor: 4.406

3.  Isolated adrenocorticotropin deficiency associated with polyglandular failure.

Authors:  I Kojima; I Nejima; E Ogata
Journal:  J Clin Endocrinol Metab       Date:  1982-01       Impact factor: 5.958

4.  Isolated corticotropin deficiency.

Authors:  Y Ichiba; T Goto
Journal:  Am J Dis Child       Date:  1983-12

5.  Isolated ACTH deficiency with transitory GH deficiency.

Authors:  Z Hochberg; D Hardoff; D Atias; A Spindel
Journal:  J Endocrinol Invest       Date:  1985-02       Impact factor: 4.256

6.  Plasma adrenocorticotropin and cortisol responses to ovine corticotropin-releasing factor in patients with adrenocortical insufficiency due to hypothalamic and pituitary disorders.

Authors:  T Tsukada; Y Nakai; T Koh; S Tsujii; M Inada; M Nishikawa; H Shinoda; I Kawai; N Takezawa; H Imura
Journal:  J Clin Endocrinol Metab       Date:  1984-04       Impact factor: 5.958

7.  Lymphoid hypophysitis with selective adrenocorticotropic hormone deficiency.

Authors:  A J Richtsmeier; R A Henry; J M Bloodworth; E N Ehrlich
Journal:  Arch Intern Med       Date:  1980-09

8.  Common variable hypogammaglobulinemia in children. Clinical and immunologic observations in 30 patients.

Authors:  C Hausser; J L Virelizier; D Buriot; C Griscelli
Journal:  Am J Dis Child       Date:  1983-09

9.  Interferon production of vitro by leucocytes from patients with systemic lupus erythematosus and rheumatoid arthritis.

Authors:  P A Neighbour; A I Grayzel
Journal:  Clin Exp Immunol       Date:  1981-09       Impact factor: 4.330

10.  Ovine (o) and human (h) corticotrophin releasing factor (CRF) in man: CRF-stimulation and CRF-immunoreactivity.

Authors:  G K Stalla; J Hartwimmer; K von Werder; O A Müller
Journal:  Acta Endocrinol (Copenh)       Date:  1984-07
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  7 in total

1.  Neurologic Complications of Common Variable Immunodeficiency.

Authors:  Jenna Thuc-Uyen Nguyen; Ari Green; Michael R Wilson; Joseph L DeRisi; Katherine Gundling
Journal:  J Clin Immunol       Date:  2016-10-04       Impact factor: 8.317

2.  Germline mutations in NFKB2 implicate the noncanonical NF-κB pathway in the pathogenesis of common variable immunodeficiency.

Authors:  Karin Chen; Emily M Coonrod; Attila Kumánovics; Zechariah F Franks; Jacob D Durtschi; Rebecca L Margraf; Wilfred Wu; Nahla M Heikal; Nancy H Augustine; Perry G Ridge; Harry R Hill; Lynn B Jorde; Andrew S Weyrich; Guy A Zimmerman; Adi V Gundlapalli; John F Bohnsack; Karl V Voelkerding
Journal:  Am J Hum Genet       Date:  2013-10-17       Impact factor: 11.025

3.  Mutations in NFKB2 and potential genetic heterogeneity in patients with DAVID syndrome, having variable endocrine and immune deficiencies.

Authors:  Thierry Brue; Marie-Hélène Quentien; Konstantin Khetchoumian; Marco Bensa; José-Mario Capo-Chichi; Brigitte Delemer; Aurelio Balsalobre; Christina Nassif; Dimitris T Papadimitriou; Anne Pagnier; Caroline Hasselmann; Lysanne Patry; Jeremy Schwartzentruber; Pierre-François Souchon; Shinobu Takayasu; Alain Enjalbert; Guy Van Vliet; Jacek Majewski; Jacques Drouin; Mark E Samuels
Journal:  BMC Med Genet       Date:  2014-12-19       Impact factor: 2.103

4.  Deficit of Anterior Pituitary Function and Variable Immune Deficiency Syndrome: A Novel Mutation.

Authors:  Pavadee Poowuttikul; Eric McGrath; Deepak Kamat
Journal:  Glob Pediatr Health       Date:  2017-01-27

5.  Novel Heterozygous Mutation in NFKB2 Is Associated With Early Onset CVID and a Functional Defect in NK Cells Complicated by Disseminated CMV Infection and Severe Nephrotic Syndrome.

Authors:  Alejandra Aird; Macarena Lagos; Alexander Vargas-Hernández; Jennifer E Posey; Zeynep Coban-Akdemir; Shalini Jhangiani; Emily M Mace; Anaid Reyes; Alejandra King; Felipe Cavagnaro; Lisa R Forbes; Ivan K Chinn; James R Lupski; Jordan S Orange; Maria Cecilia Poli
Journal:  Front Pediatr       Date:  2019-07-30       Impact factor: 3.418

6.  Common variable immune deficiency, central diabetes insipidus, and anemia.

Authors:  Marta Baleva; Spaska Lesichkova; Nevena Gesheva; Snejina Mihailova; Vanya Gerova; Borislav Vladimirov; Plamen Penchev; Milena Nikolova-Vlahova; Elissaveta Naumova
Journal:  Cent Eur J Immunol       Date:  2020-11-01       Impact factor: 2.085

7.  Endocrine Disorders Are Prominent Clinical Features in Patients With Primary Antibody Deficiencies.

Authors:  Eva C Coopmans; Paweena Chunharojrith; Sebastian J C M M Neggers; Marianne W van der Ent; Sigrid M A Swagemakers; Iris H Hollink; Barbara H Barendregt; Peter J van der Spek; Aart-Jan van der Lely; P Martin van Hagen; Virgil A S H Dalm
Journal:  Front Immunol       Date:  2019-08-30       Impact factor: 7.561
  7 in total

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