Literature DB >> 16455303

What causes lymphocyte hyporesponsiveness during filarial nematode infection?

William Harnett1, Margaret M Harnett.   

Abstract

Filarial nematodes persist in the parasitized host by modulating immune responsiveness. A feature of this that has been observed in a multitude of studies dating back several decades is an inability of lymphocytes to respond appropriately to filarial nematode antigens and, in some cases, to other stimuli. The consistency of this observation, allied to the ease of measurement of lymphocyte hyporesponsiveness, has resulted in many attempts to understand its cause.

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Year:  2006        PMID： 16455303     DOI： 10.1016/j.pt.2006.01.010

Source DB:  PubMed          Journal:  Trends Parasitol        ISSN： 1471-4922


  6 in total

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  6 in total

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