Literature DB >> 16455245

Novel skeleton terpenes from Celastrus hypoleucus with anti-tumor activities.

Kui-wu Wang1, Jian-shan Mao, Yuan-po Tai, Yuan-jiang Pan.   

Abstract

Celahypodiol 1, an unusual 17-membered carbon diterpenoid with a novel skeleton, and a new triterpenoid 12-oleanene-3beta,6alpha-diol 2, together with four known compounds furreginol 3, suigol 4, 20(30)-lupene-3beta, 29-diol 5, and 20(29)-lupene-1beta,3beta-diol 6, were isolated from the stalks of Celastrus hypoleucus (Oliv.) Warb. Their structures were established by means of spectroscopic analysis, including 2D NMR. The new compounds exhibited anti-tumor activities against a panel of human tumor cell lines.

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Year:  2006        PMID: 16455245     DOI: 10.1016/j.bmcl.2006.01.021

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  3 in total

1.  Celastrol and Its Role in Controlling Chronic Diseases.

Authors:  Shivaprasad H Venkatesha; Kamal D Moudgil
Journal:  Adv Exp Med Biol       Date:  2016       Impact factor: 2.622

2.  Triterpenoids from Celastrus orbiculatus Thunb. inhibit RANKL-induced osteoclast formation and bone resorption via c-Fos signaling.

Authors:  Thi Oanh Vu; Phuong Thao Tran; Wonyoung Seo; Jeong Hyung Lee; Byung Sun Min; Jeong Ah Kim
Journal:  J Nat Med       Date:  2020-08-10       Impact factor: 2.343

3.  A new friedelane type triterpene from Euonymus hederaceus.

Authors:  Cui-Rong Sun; He-Jiao Hu; Run-Sheng Xu; Jie-Hong Yang; Hai-Tong Wan
Journal:  Molecules       Date:  2009-07-17       Impact factor: 4.411

  3 in total

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