| Literature DB >> 16455241 |
Jamie L Cohen1, Agenor Limon, Ricardo Miledi, A Richard Chamberlin.
Abstract
The design and synthesis of four 2,2-disubstituted dihydrobenzofurans that are structurally related to several glutamate-containing natural products, including (-)-dysiherbaine, is described. Biological evaluation of these analogs shows that one is a KA receptor antagonist and another is an NMDA receptor agonist.Entities:
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Year: 2006 PMID： 16455241 DOI： 10.1016/j.bmcl.2006.01.047
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823