Literature DB >> 16453162

Molecular and biochemical characterization of kettin in Caenorhabditis elegans.

Shoichiro Ono1, Kurato Mohri, Kanako Ono.   

Abstract

Kettin is a unique member of the connectin/titin family of muscle elastic proteins, which has repetitive immunoglobulin-like domains that are separated by weakly conserved linker sequences. In striated muscles of insects and crayfish, kettin binds to actin filaments and localizes to the Z-disc and its adjacent region in the I-band. Recent sequence analysis of invertebrate connectin/titin (also known as SLS proteins) has revealed that kettin is a splice variant of connectin/titin. In contrast, in the nematode Caenorhabditis elegans, the kettin gene is independent of the genes for other connectin/titin-related proteins. Immunofluorescent localization of kettin shows that it localizes to the I-bands in the obliquely striated body wall muscle. Therefore, C. elegans is an attractive model system to study specific functions of kettin in muscle cells.

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Year:  2005        PMID： 16453162     DOI： 10.1007/s10974-005-9028-3

Source DB:  PubMed          Journal:  J Muscle Res Cell Motil        ISSN： 0142-4319            Impact factor:   2.698


  48 in total

1.  Invertebrate connectin spans as much as 3.5 microm in the giant sarcomeres of crayfish claw muscle.

Authors:  A Fukuzawa; J Shimamura; S Takemori; N Kanzawa; M Yamaguchi; P Sun; K Maruyama; S Kimura
Journal:  EMBO J       Date:  2001-09-03       Impact factor: 11.598

Review 2.  Defining actin filament length in striated muscle: rulers and caps or dynamic stability?

Authors:  R Littlefield; V M Fowler
Journal:  Annu Rev Cell Dev Biol       Date:  1998       Impact factor: 13.827

3.  Titins in C.elegans with unusual features: coiled-coil domains, novel regulation of kinase activity and two new possible elastic regions.

Authors:  Denise B Flaherty; Kim M Gernert; Nataliya Shmeleva; Xuexin Tang; Kristina B Mercer; Mark Borodovsky; Guy M Benian
Journal:  J Mol Biol       Date:  2002-10-25       Impact factor: 5.469

4.  Mutations in the dystrophin-like dys-1 gene of Caenorhabditis elegans result in reduced acetylcholinesterase activity.

Authors:  J Giugia; K Gieseler; M Arpagaus; L Ségalat
Journal:  FEBS Lett       Date:  1999-12-17       Impact factor: 4.124

5.  Actin filament disassembling activity of Caenorhabditis elegans actin-interacting protein 1 (UNC-78) is dependent on filament binding by a specific ADF/cofilin isoform.

Authors:  Kurato Mohri; Shoichiro Ono
Journal:  J Cell Sci       Date:  2003-09-02       Impact factor: 5.285

6.  Association of kettin with actin in the Z-disc of insect flight muscle.

Authors:  M van Straaten; D Goulding; B Kolmerer; S Labeit; J Clayton; K Leonard; B Bullard
Journal:  J Mol Biol       Date:  1999-01-29       Impact factor: 5.469

7.  Muscle organization in Caenorhabditis elegans: localization of proteins implicated in thin filament attachment and I-band organization.

Authors:  G R Francis; R H Waterston
Journal:  J Cell Biol       Date:  1985-10       Impact factor: 10.539

8.  Genes critical for muscle development and function in Caenorhabditis elegans identified through lethal mutations.

Authors:  B D Williams; R H Waterston
Journal:  J Cell Biol       Date:  1994-02       Impact factor: 10.539

Review 9.  Varieties of elastic protein in invertebrate muscles.

Authors:  Belinda Bullard; Wolfgang A Linke; Kevin Leonard
Journal:  J Muscle Res Cell Motil       Date:  2002       Impact factor: 3.352

10.  Myosin and paramyosin of Caenorhabditis elegans embryos assemble into nascent structures distinct from thick filaments and multi-filament assemblages.

Authors:  H F Epstein; D L Casey; I Ortiz
Journal:  J Cell Biol       Date:  1993-08       Impact factor: 10.539
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  6 in total

Review 1.  Regulation of structure and function of sarcomeric actin filaments in striated muscle of the nematode Caenorhabditis elegans.

Authors:  Shoichiro Ono
Journal:  Anat Rec (Hoboken)       Date:  2014-09       Impact factor: 2.064

2.  Kettin, the large actin-binding protein with multiple immunoglobulin domains, is essential for sarcomeric actin assembly and larval development in Caenorhabditis elegans.

Authors:  Kanako Ono; Zhaozhao Qin; Robert C Johnsen; David L Baillie; Shoichiro Ono
Journal:  FEBS J       Date:  2019-08-24       Impact factor: 5.542

3.  Caenorhabditis elegans kettin, a large immunoglobulin-like repeat protein, binds to filamentous actin and provides mechanical stability to the contractile apparatuses in body wall muscle.

Authors:  Kanako Ono; Robinson Yu; Kurato Mohri; Shoichiro Ono
Journal:  Mol Biol Cell       Date:  2006-04-05       Impact factor: 4.138

4.  Structural components of the nonstriated contractile apparatuses in the Caenorhabditis elegans gonadal myoepithelial sheath and their essential roles for ovulation.

Authors:  Kanako Ono; Robinson Yu; Shoichiro Ono
Journal:  Dev Dyn       Date:  2007-04       Impact factor: 3.780

Review 5.  Dynamic regulation of sarcomeric actin filaments in striated muscle.

Authors:  Shoichiro Ono
Journal:  Cytoskeleton (Hoboken)       Date:  2010-11

6.  The ALP-Enigma protein ALP-1 functions in actin filament organization to promote muscle structural integrity in Caenorhabditis elegans.

Authors:  Hsiao-Fen Han; Mary C Beckerle
Journal:  Mol Biol Cell       Date:  2009-03-04       Impact factor: 4.138
  6 in total

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