Literature DB >> 16452347

Risk of intracranial pathologic conditions requiring emergency intervention after a first complex febrile seizure episode among children.

David Teng1, Peter Dayan, Sarah Tyler, W Allen Hauser, Stephen Chan, Linda Leary, Dale Hesdorffer.   

Abstract

OBJECTIVE: To determine the likelihood of intracranial pathologic conditions requiring emergency neurosurgical or medical intervention among children without meningitis who presented to the pediatric emergency department after a first complex febrile seizure.
METHODS: We performed a retrospective review of prospectively collected data for children in neurologically normal condition who presented to a single pediatric emergency department after a first complex febrile seizure (focal, multiple, or prolonged). The complex febrile seizure classification was determined independently by 2 epileptologists. The presence of intracranial pathologic conditions was determined through review of neuroimaging results, telephone interviews, or medical record review.
RESULTS: Data for 71 children with first complex febrile seizures were analyzed. Fifty-one (72%) had a single complex feature (20 focal, 22 multiple, and 9 prolonged), and 20 (28%) had multiple complex features. None of the 71 patients (1-sided 95% confidence interval: 4%) had intracranial pathologic conditions that required emergency neurosurgical or medical intervention.
CONCLUSIONS: For children with first complex febrile seizures, the risk of intracranial pathologic conditions that require emergency neurosurgical or medical intervention is low, which suggests that routine emergency neuroimaging for this population is unnecessary.

Entities:  

Mesh:

Year:  2006        PMID: 16452347     DOI: 10.1542/peds.2005-0759

Source DB:  PubMed          Journal:  Pediatrics        ISSN: 0031-4005            Impact factor:   7.124


  8 in total

Review 1.  Febrile seizures.

Authors:  Lynette G Sadleir; Ingrid E Scheffer
Journal:  BMJ       Date:  2007-02-10

2.  The baseline risk of multiple febrile seizures in the same febrile illness: a meta-analysis.

Authors:  Christopher Henry; Chelsea Cockburn; Mary Helen Simpson; Serenity Budd; Chen Wang; Darina Dinov
Journal:  Eur J Pediatr       Date:  2022-03-16       Impact factor: 3.860

Review 3.  Actual insights into the clinical management of febrile seizures.

Authors:  Mario Mastrangelo; Fabio Midulla; Corrado Moretti
Journal:  Eur J Pediatr       Date:  2014-01-30       Impact factor: 3.183

4.  Febrile seizures in one-five aged infants in tropical practice: Frequency, etiology and outcome of hospitalization.

Authors:  Komi Assogba; Bahoura Balaka; Fidato A Touglo; Kossivi M Apetsè; Damelan Kombaté
Journal:  J Pediatr Neurosci       Date:  2015 Jan-Mar

Review 5.  Febrile seizures: A review.

Authors:  Wesley Eilbert; Chuck Chan
Journal:  J Am Coll Emerg Physicians Open       Date:  2022-08-23

6.  Necessity of lumbar puncture in patients presenting with new onset complex febrile seizures.

Authors:  Erin M Fletcher; Ghazala Sharieff
Journal:  West J Emerg Med       Date:  2013-05

7.  Is There Any Need for Emergency Neuroimaging in Children With first Complex Febrile Seizure?

Authors:  Afagh Hassanzadeh Rad; Manijeh Tabrizi; Peyman Dadashzadeh; Vahid Aminzadeh
Journal:  Iran J Child Neurol       Date:  2020

8.  Clinical Features and Evaluation in Terms of Prophylaxis of Patients With Febrile Seizures.

Authors:  Betül Kılıç
Journal:  Sisli Etfal Hastan Tip Bul       Date:  2019-08-27
  8 in total

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