Literature DB >> 16452164

Protein-protein interactions for cancer therapy.

Curtis C Harris1.   

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Year:  2006        PMID： 16452164      PMCID： PMC1413676          DOI： 10.1073/pnas.0510948103

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


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  20 in total

Review 1.  Small-molecule inhibitors of the p53 suppressor HDM2: have protein-protein interactions come of age as drug targets?

Authors:  Peter M Fischer; David P Lane
Journal:  Trends Pharmacol Sci       Date:  2004-07       Impact factor: 14.819

2.  Modulation of mammalian life span by the short isoform of p53.

Authors:  Bernhard Maier; Wendy Gluba; Brian Bernier; Terry Turner; Khalid Mohammad; Theresa Guise; Ann Sutherland; Michael Thorner; Heidi Scrable
Journal:  Genes Dev       Date:  2004-02-01       Impact factor: 11.361

Review 3.  Intrinsic tumour suppression.

Authors:  Scott W Lowe; Enrique Cepero; Gerard Evan
Journal:  Nature       Date:  2004-11-18       Impact factor: 49.962

4.  Overexpression of Mdm2 in mice reveals a p53-independent role for Mdm2 in tumorigenesis.

Authors:  S N Jones; A R Hancock; H Vogel; L A Donehower; A Bradley
Journal:  Proc Natl Acad Sci U S A       Date:  1998-12-22       Impact factor: 11.205

5.  Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain.

Authors:  P H Kussie; S Gorina; V Marechal; B Elenbaas; J Moreau; A J Levine; N P Pavletich
Journal:  Science       Date:  1996-11-08       Impact factor: 47.728

6.  Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours.

Authors:  L A Donehower; M Harvey; B L Slagle; M J McArthur; C A Montgomery; J S Butel; A Bradley
Journal:  Nature       Date:  1992-03-19       Impact factor: 49.962

Review 7.  p53 mutations in human cancers.

Authors:  M Hollstein; D Sidransky; B Vogelstein; C C Harris
Journal:  Science       Date:  1991-07-05       Impact factor: 47.728

8.  MDM2 is a negative regulator of p21WAF1/CIP1, independent of p53.

Authors:  Zhuo Zhang; Hui Wang; Mao Li; Sudhir Agrawal; Xinbin Chen; Ruiwen Zhang
Journal:  J Biol Chem       Date:  2004-02-03       Impact factor: 5.157

9.  In vivo activation of the p53 pathway by small-molecule antagonists of MDM2.

Authors:  Lyubomir T Vassilev; Binh T Vu; Bradford Graves; Daisy Carvajal; Frank Podlaski; Zoran Filipovic; Norman Kong; Ursula Kammlott; Christine Lukacs; Christian Klein; Nader Fotouhi; Emily A Liu
Journal:  Science       Date:  2004-01-02       Impact factor: 47.728

Review 10.  The MDM2 gene amplification database.

Authors:  J Momand; D Jung; S Wilczynski; J Niland
Journal:  Nucleic Acids Res       Date:  1998-08-01       Impact factor: 16.971
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  6 in total

1.  Catalytic, Enantioselective Synthesis of Stilbene cis-Diamines: A Concise Preparation of (-)-Nutlin-3, a Potent p53/MDM2 Inhibitor.

Authors:  Tyler A Davis; Jeffrey N Johnston
Journal:  Chem Sci       Date:  2011-03-25       Impact factor: 9.825

2.  Functional inhibition of c-Myc using novel inhibitors identified through "hot spot" targeting.

Authors:  Ashutosh Singh; Prateek Kumar; Sailu Sarvagalla; Taniya Bharadwaj; Namyashree Nayak; Mohane Selvaraj Coumar; Rajanish Giri; Neha Garg
Journal:  J Biol Chem       Date:  2022-04-01       Impact factor: 5.486

3.  ATHENA: Identifying interactions between different levels of genomic data associated with cancer clinical outcomes using grammatical evolution neural network.

Authors:  Dokyoon Kim; Ruowang Li; Scott M Dudek; Marylyn D Ritchie
Journal:  BioData Min       Date:  2013-12-20       Impact factor: 2.522

Review 4.  Targeting oncogenic protein-protein interactions by diversity oriented synthesis and combinatorial chemistry approaches.

Authors:  Andreas G Tzakos; Demosthenes Fokas; Charlie Johannes; Vassilios Moussis; Eleftheria Hatzimichael; Evangelos Briasoulis
Journal:  Molecules       Date:  2011-05-27       Impact factor: 4.411

5.  A Quantitative Systems Approach to Define Novel Effects of Tumour p53 Mutations on Binding Oncoprotein MDM2.

Authors:  Manuel Fuentes; Sanjeeva Srivastava; Angela M Gronenborn; Joshua LaBaer
Journal:  Int J Mol Sci       Date:  2021-12-21       Impact factor: 5.923

6.  Molecular mechanisms of nutlin-3 involve acetylation of p53, histones and heat shock proteins in acute myeloid leukemia.

Authors:  Ingvild Haaland; Jill A Opsahl; Frode S Berven; Håkon Reikvam; Hanne K Fredly; Ragnhild Haugse; Bernd Thiede; Emmet McCormack; Sonia Lain; Oystein Bruserud; Bjørn Tore Gjertsen
Journal:  Mol Cancer       Date:  2014-05-21       Impact factor: 27.401
  6 in total

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