| Literature DB >> 16451192 |
Maya Elgrably-Weiss1, Eliana Schlosser-Silverman, Ilan Rosenshine, Shoshy Altuvia.
Abstract
In this study, we investigated the genetic organization and function of Escherichia coli yciT, a gene predicted by computational methods to belong to the DeoR-type family of transcriptional regulators. We show that transcription of yciT (here denoted deoT for deoR-Type) initiates from a promoter located upstream of a putative open reading frame (denoted deoL for deoT Leader). We also show that DeoT acts as a global regulator, repressing the expression of a number of genes involved in a variety of metabolic pathways including transport of maltose, fatty acid beta-oxidation and peptide degradation.Entities:
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Year: 2006 PMID: 16451192 DOI: 10.1111/j.1574-6968.2005.00020.x
Source DB: PubMed Journal: FEMS Microbiol Lett ISSN: 0378-1097 Impact factor: 2.742