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Literature DB >> 164502

Respiratory and humoral immune response to aerosol and intramuscular pertussis vaccine.

Abstract

Animal experiments have shown that respiratory administration of pertussis antigen induces a protective immune response. In this study pertussis antibody in human respiratory secretions was measured and the response to aerosol and intramuscular pertussis immunization investigated. Substanial increases in this antibody occurred after aerosol immunization but no changes were found in serum antibody. The reverse was observed after intramuscular pertussis vaccine in adults but not with aerosol immunization. The latter method may be of value for paediatric medical and nursing personnel exposed to the risk of pertussis infection.

Entities: Disease Species

Mesh：

Substances：

Year: 1975 PMID： 164502 PMCID： PMC2130377 DOI： 10.1017/s0022172400024293

Source DB: PubMed Journal: J Hyg (Lond) ISSN： 0022-1724

9 in total

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Authors: G N COOPER
Journal: J Pathol Bacteriol Date: 1952-01

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Authors: L B Holt
Journal: J Med Microbiol Date: 1972-11 Impact factor: 2.472

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Authors: J D Rosenthal; K Hayashi; A L Notkins
Journal: J Immunol Date: 1972-07 Impact factor: 5.422

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Authors: R H Waldman; J J Mann; J A Kasel
Journal: J Immunol Date: 1968-01 Impact factor: 5.422

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Authors: R H Alford; R D Rossen; W T Butler; J A Kasel
Journal: J Immunol Date: 1967-04 Impact factor: 5.422

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Authors: J J Mann; R H Waldman; Y Togo; G G Heiner; A T Dawkins; J A Kasel
Journal: J Immunol Date: 1968-04 Impact factor: 5.422

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Authors: J A Kasel; E B Hume; R V Fulk; Y Togo; M Huber; R B Hornick
Journal: J Immunol Date: 1969-03 Impact factor: 5.422

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Authors: J D Abbott; N W Preston; R I Mackay
Journal: Br Med J Date: 1971-01-09

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Authors: T B TOMASI; E M TAN; A SOLOMON; R A PRENDERGAST
Journal: J Exp Med Date: 1965-01-01 Impact factor: 14.307

9 in total

1. Pertussis: epidemiology and control.

Authors: A S Muller; J Leeuwenburg; D S Pratt
Journal: Bull World Health Organ Date: 1986 Impact factor: 9.408

2. The serological diagnosis of whooping cough.

Authors: M E Macaulay
Journal: J Hyg (Lond) Date: 1979-08

3. Mucosal immunization with filamentous hemagglutinin protects against Bordetella pertussis respiratory infection.

Authors: R D Shahin; D F Amsbaugh; M F Leef
Journal: Infect Immun Date: 1992-04 Impact factor: 3.441

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Authors: Y E Goodman; A J Wort; F L Jackson
Journal: J Clin Microbiol Date: 1981-02 Impact factor: 5.948

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Authors: L A Ashworth; R B Fitzgeorge; L I Irons; C P Morgan; A Robinson
Journal: J Hyg (Lond) Date: 1982-06