Literature DB >> 16449709

Long-term outcome of two forms of randomised benzodiazepine discontinuation.

R C Oude Voshaar1, W J M J Gorgels, A J J Mol, A J L M van Balkom, J Mulder, E H van de Lisdonk, M H M Breteler, F G Zitman.   

Abstract

About two-thirds of long-term users of benzodiazepines in the population are able to discontinue this drug with the aid of supervised programmes for tapering off. Little is known about the long-term outcome of such programmes, and they have never been compared with usual care. After a 15-month follow-up of a randomised controlled trial comparing such a programme with and without psychotherapy with usual care, we found significantly higher longitudinal abstinence rates in long-term benzodiazepine users who received a benzodiazepine tapering-off programme without psychotherapy (25 out of 69, 36%) compared with those who received usual care (5 out of 33,15%; P=0.03).

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Year:  2006        PMID: 16449709     DOI: 10.1192/bjp.bp.105.012039

Source DB:  PubMed          Journal:  Br J Psychiatry        ISSN: 0007-1250            Impact factor:   9.319


  7 in total

1.  Tapering off benzodiazepines in long-term users: an economic evaluation.

Authors:  Richard C Oude Voshaar; Paul F M Krabbe; Wim J M J Gorgels; Eddy M M Adang; Anton J L M van Balkom; Eloy H van de Lisdonk; Frans G Zitman
Journal:  Pharmacoeconomics       Date:  2006       Impact factor: 4.981

Review 2.  Withdrawing Benzodiazepines in Patients With Anxiety Disorders.

Authors:  Malcolm Lader; Andri Kyriacou
Journal:  Curr Psychiatry Rep       Date:  2016-01       Impact factor: 5.285

3.  Prescribing ANtiDepressants Appropriately (PANDA): a cluster randomized controlled trial in primary care.

Authors:  Esther Muskens; Rhona Eveleigh; Peter Lucassen; Chris van Weel; Jan Spijker; Peter Verhaak; Anne Speckens; Richard Oude Voshaar
Journal:  BMC Fam Pract       Date:  2013-01-08       Impact factor: 2.497

4.  Prescribing antidepressants and benzodiazepines in the Netherlands: is chronic physical illness involved?

Authors:  Jacques Th M van Eijk; Hans Bosma; Catharina C M Jonkers; Femke Lamers; Paul E M Muijrers
Journal:  Depress Res Treat       Date:  2010-02-07

5.  Withdrawal of unnecessary antidepressant medication: a randomised controlled trial in primary care.

Authors:  Rhona Eveleigh; Esther Muskens; Peter Lucassen; Peter Verhaak; Jan Spijker; Chris van Weel; Richard Oude Voshaar; Anne Speckens
Journal:  BJGP Open       Date:  2017-11-15

6.  Evolution of benzodiazepine receptor agonist prescriptions in general practice: A registry-based study.

Authors:  Kristien Coteur; Pavlos Mamouris; Bert Vaes; Marc Van Nuland; Catharina Matheï; Birgitte Schoenmakers
Journal:  Front Public Health       Date:  2022-09-23

7.  Patient-centered care interventions to reduce the inappropriate prescription and use of benzodiazepines and z-drugs: a systematic review.

Authors:  Aliaksandra Mokhar; Janine Topp; Martin Härter; Holger Schulz; Silke Kuhn; Uwe Verthein; Jörg Dirmaier
Journal:  PeerJ       Date:  2018-10-08       Impact factor: 2.984

  7 in total

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