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Literature DB >> 16449694

Two-week delay in onset of action of antidepressants: new evidence.

Abstract

Many sources purport that antidepressants have a delayed onset of action, measured in weeks rather than days. Recent data using weekly or daily mood ratings demonstrate that maximum improvement occurs during the first 2 weeks, with some improvement within the first 3 days. Methodological issues may underlie the delayed-onset hypothesis.

Mesh：

Substances：
Antidepressive Agents

Year: 2006 PMID： 16449694 DOI： 10.1192/bjp.bp.105.011692

Source DB: PubMed Journal: Br J Psychiatry ISSN： 0007-1250 Impact factor: 9.319

Keyword Cloud
Cited

18 in total

Review 1. Glutamate receptor ion channels: structure, regulation, and function.

Authors: Stephen F Traynelis; Lonnie P Wollmuth; Chris J McBain; Frank S Menniti; Katie M Vance; Kevin K Ogden; Kasper B Hansen; Hongjie Yuan; Scott J Myers; Ray Dingledine
Journal: Pharmacol Rev Date: 2010-09 Impact factor: 25.468

Review 2. Pharmacogenetics of antidepressant response.

Authors: Stefano Porcelli; Antonio Drago; Chiara Fabbri; Sara Gibiino; Raffaella Calati; Alessandro Serretti
Journal: J Psychiatry Neurosci Date: 2011-03 Impact factor: 6.186

3. A Computational Model of Major Depression: the Role of Glutamate Dysfunction on Cingulo-Frontal Network Dynamics.

Authors: Juan P Ramirez-Mahaluf; Alexander Roxin; Helen S Mayberg; Albert Compte
Journal: Cereb Cortex Date: 2017-01-01 Impact factor: 5.357

4. Social fear conditioning: a novel and specific animal model to study social anxiety disorder.

Authors: Iulia Toth; Inga D Neumann; David A Slattery
Journal: Neuropsychopharmacology Date: 2012-01-11 Impact factor: 7.853

5. Analysis of region-specific changes in gene expression upon treatment with citalopram and desipramine reveals temporal dynamics in response to antidepressant drugs at the transcriptome level.

Authors: Magdalena Gąska; Maciej Kuśmider; Joanna Solich; Agata Faron-Górecka; Małgorzata J Krawczyk; Krzysztof Kułakowski; Marta Dziedzicka-Wasylewska
Journal: Psychopharmacology (Berl) Date: 2012-05-01 Impact factor: 4.530

Two-week delay in onset of action of antidepressants: new evidence.

Review 1. Glutamate receptor ion channels: structure, regulation, and function.

Review 2. Pharmacogenetics of antidepressant response.

3. A Computational Model of Major Depression: the Role of Glutamate Dysfunction on Cingulo-Frontal Network Dynamics.

4. Social fear conditioning: a novel and specific animal model to study social anxiety disorder.

5. Analysis of region-specific changes in gene expression upon treatment with citalopram and desipramine reveals temporal dynamics in response to antidepressant drugs at the transcriptome level.

6. Initial rate of improvement in relation to remission of major depressive disorder in primary care.

7. Oppositional effects of serotonin receptors 5-HT1a, 2, and 2c in the regulation of adult hippocampal neurogenesis.

8. Association of Novel ALX4 Gene Polymorphisms with Antidepressant Treatment Response: Findings from the CO-MED Trial.

Review 9. Translating the promise of 5HT₄ receptor agonists for the treatment of depression.

Review 10. Elucidating the Possible Role of FoxO in Depression.

Two-week delay in onset of action of antidepressants: new evidence.

Review 1. Glutamate receptor ion channels: structure, regulation, and function.

Review 2. Pharmacogenetics of antidepressant response.

3. A Computational Model of Major Depression: the Role of Glutamate Dysfunction on Cingulo-Frontal Network Dynamics.

4. Social fear conditioning: a novel and specific animal model to study social anxiety disorder.

5. Analysis of region-specific changes in gene expression upon treatment with citalopram and desipramine reveals temporal dynamics in response to antidepressant drugs at the transcriptome level.

6. Initial rate of improvement in relation to remission of major depressive disorder in primary care.

7. Oppositional effects of serotonin receptors 5-HT1a, 2, and 2c in the regulation of adult hippocampal neurogenesis.

8. Association of Novel ALX4 Gene Polymorphisms with Antidepressant Treatment Response: Findings from the CO-MED Trial.

Review 9. Translating the promise of 5HT4 receptor agonists for the treatment of depression.

Review 10. Elucidating the Possible Role of FoxO in Depression.

Review 9. Translating the promise of 5HT₄ receptor agonists for the treatment of depression.