AIMS: To determine whether the monitoring of respiratory disease progression in children with cystic fibrosis (CF) can be made using six pre-selected computed tomography (CT) cuts in lieu of the conventional full study. METHODS: Forty one lung CT scans from 21 paediatric patients with CF were analysed. The Bhalla and Nathanson scores of the total lung CT and the six pre-selected CT cuts were compared. RESULTS: The Bhalla mean score of the total lung CT evaluated by two radiologists was 5.62. It was 5.36 when just the six pre-selected sections were evaluated. The difference between means was not statistically significant. The Nathanson mean score of the total lung CT evaluated by both radiologists was 66.11; it was 66.51 when just the six pre-selected sections were evaluated. The difference between means was not statistically significant. The mean total radiation dose from a single whole lung CT scan was 716.22 mGy.cm. A dose of 250.66 mGy.cm was estimated if only six sections were used, with a reduction in radiation of about 65%. CONCLUSION: It is possible to obtain the same radiological information from six pre-selected CT cuts as it is from a full pulmonary CT scan, thereby markedly reducing radiation exposure for children who will require repeat investigations in the future.
AIMS: To determine whether the monitoring of respiratory disease progression in children with cystic fibrosis (CF) can be made using six pre-selected computed tomography (CT) cuts in lieu of the conventional full study. METHODS: Forty one lung CT scans from 21 paediatric patients with CF were analysed. The Bhalla and Nathanson scores of the total lung CT and the six pre-selected CT cuts were compared. RESULTS: The Bhalla mean score of the total lung CT evaluated by two radiologists was 5.62. It was 5.36 when just the six pre-selected sections were evaluated. The difference between means was not statistically significant. The Nathanson mean score of the total lung CT evaluated by both radiologists was 66.11; it was 66.51 when just the six pre-selected sections were evaluated. The difference between means was not statistically significant. The mean total radiation dose from a single whole lung CT scan was 716.22 mGy.cm. A dose of 250.66 mGy.cm was estimated if only six sections were used, with a reduction in radiation of about 65%. CONCLUSION: It is possible to obtain the same radiological information from six pre-selected CT cuts as it is from a full pulmonary CT scan, thereby markedly reducing radiation exposure for children who will require repeat investigations in the future.
Authors: Pim A de Jong; Yasutaka Nakano; Wim C Hop; Frederick R Long; Harvey O Coxson; Peter D Paré; Harm A Tiddens Journal: Am J Respir Crit Care Med Date: 2005-04-14 Impact factor: 21.405
Authors: T H Helbich; G Heinz-Peer; I Eichler; P Wunderbaldinger; M Götz; C Wojnarowski; R C Brasch; C J Herold Journal: Radiology Date: 1999-11 Impact factor: 11.105
Authors: Alan S Brody; Harm A W M Tiddens; Robert G Castile; Harvey O Coxson; Pim A de Jong; Jonathan Goldin; Walter Huda; Frederick R Long; Michael McNitt-Gray; Michael Rock; Terry E Robinson; Scott D Sagel Journal: Am J Respir Crit Care Med Date: 2005-08-11 Impact factor: 21.405
Authors: Pim A de Jong; Mark D Ottink; Simon G F Robben; Maarten H Lequin; Wim C J Hop; Johan J E Hendriks; Peter D Paré; Harm A W M Tiddens Journal: Radiology Date: 2004-04-02 Impact factor: 11.105