Literature DB >> 1644878

Human monoclonal antibodies: achievement and potential.

D R Burton1.   

Abstract

The concept of monoclonal antibodies evoked great excitement when first described, but usefulness has been limited by their murine origin and consequent immunogenicity. Human monoclonal antibodies which would obviate xenotypic responses-can now be produced. Clinical implications-including use against HIV-are discussed.

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Year:  1992        PMID： 1644878     DOI： 10.1080/21548331.1992.11705469

Source DB:  PubMed          Journal:  Hosp Pract (Off Ed)        ISSN： 8750-2836


  1 in total

1.  Directed selection of recombinant human monoclonal antibodies to herpes simplex virus glycoproteins from phage display libraries.

Authors:  P P Sanna; R A Williamson; A De Logu; F E Bloom; D R Burton
Journal:  Proc Natl Acad Sci U S A       Date:  1995-07-03       Impact factor: 11.205
  1 in total

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