Literature DB >> 16446840

Fluorinase mediated C-(18)F bond formation, an enzymatic tool for PET labelling.

Hai Deng1, Steven L Cobb, Antony D Gee, Andrew Lockhart, Laurent Martarello, Ryan P McGlinchey, David O'Hagan, Mayca Onega.   

Abstract

The fluorinase enzyme from S. cattleya is applied as a catalyst for the efficient incorporation of [18F]-fluoride into [18F]-5'-fluoro-5'-deoxyadenosine, [18F]-5'-fluoro-5'-deoxyinosine and [18F]-5-fluoro-5-deoxyribose for positron emission tomography (PET) applications.

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Year:  2006        PMID： 16446840     DOI： 10.1039/b516861a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  6 in total

Review 1.  Modular strategies for PET imaging agents.

Authors:  Jacob M Hooker
Journal:  Curr Opin Chem Biol       Date:  2009-10-31       Impact factor: 8.822

Review 2.  Radiosyntheses using fluorine-18: the art and science of late stage fluorination.

Authors:  Erin L Cole; Megan N Stewart; Ryan Littich; Raphael Hoareau; Peter J H Scott
Journal:  Curr Top Med Chem       Date:  2014       Impact factor: 3.295

3.  Substrate specificity in enzymatic fluorination. The fluorinase from Streptomyces cattleya accepts 2'-deoxyadenosine substrates.

Authors:  Steven L Cobb; Hai Deng; Andrew R McEwan; James H Naismith; David O'Hagan; David A Robinson
Journal:  Org Biomol Chem       Date:  2006-03-08       Impact factor: 3.876

Review 4.  Recent Trends in the Nucleophilic [(18)F]-radiolabeling Method with No-carrier-added [(18)F]fluoride.

Authors:  Dong Wook Kim; Hwan-Jeong Jeong; Seok Tae Lim; Myung-Hee Sohn
Journal:  Nucl Med Mol Imaging       Date:  2010-02-26

5.  Characterization of a SAM-dependent fluorinase from a latent biosynthetic pathway for fluoroacetate and 4-fluorothreonine formation in Nocardia brasiliensis.

Authors:  Yaya Wang; Zixin Deng; Xudong Qu
Journal:  F1000Res       Date:  2014-02-19

Review 6.  Structural perspective on enzymatic halogenation.

Authors:  Leah C Blasiak; Catherine L Drennan
Journal:  Acc Chem Res       Date:  2009-01-20       Impact factor: 22.384
  6 in total

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