Literature DB >> 1644667

Inhibition of B6RV2 leukemia growth by immunization with purified unique antigen.

A Uenaka1, E Nakayama.   

Abstract

Monoclonal antibody (mAb) NU7-99 reacted with only B6RV2 cells, not with 28 other leukemia cell lines, fibroblasts or normal tissues. Biochemical analyses of the unique antigen on B6RV2 cells that reacted with NU7-99 mAb indicated its relationship to xenotropic murine leukemia virus gp70. The antigen that reacted with NU7-99 mAb was extracted from the surface of B6RV2 cells with n-butanol and purified by ion-exchange chromatography and affinity chromatography. Growth of B6RV2 tumors in semi-syngeneic mice was inhibited by immunization of the mice with a purified preparation of this unique antigen.

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Year:  1992        PMID： 1644667      PMCID： PMC5918884          DOI： 10.1111/j.1349-7006.1992.tb00139.x

Source DB:  PubMed          Journal:  Jpn J Cancer Res        ISSN： 0910-5050


radiation leukemia virus monoclonal antibody murine leukemia virus C57BL/6 (BALB/c×C57BL/6)F1 enzyme‐linked immunosorbent assay relative salt concentration (p‐amidinophenyl)methanesulfonyl fluoride hydro‐chloride sodium dodecyl sulfate polyacrylamide gel electrophoresis
  18 in total

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Authors:  E Nakayama; A Uenaka; E Stockert; Y Obata
Journal:  Cancer Res       Date:  1984-11       Impact factor: 12.701

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Journal:  Proc Natl Acad Sci U S A       Date:  1986-05       Impact factor: 11.205

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Authors:  G C DuBois; L W Law
Journal:  Int J Cancer       Date:  1986-06-15       Impact factor: 7.396

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Authors:  S J LeGrue; B D Kahan; N R Pellis
Journal:  J Natl Cancer Inst       Date:  1980-07       Impact factor: 13.506

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Authors:  P K Srivastava; Y T Chen; L J Old
Journal:  Proc Natl Acad Sci U S A       Date:  1987-06       Impact factor: 11.205

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Journal:  J Exp Med       Date:  1986-02-01       Impact factor: 14.307
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