Literature DB >> 16445669

Clinical significance of N-acetyl-L-aspartate resonance in ovarian mucinous cystadenoma.

S Hascalik1, O Celik, K Sarac, A Alkan, B Mizrak.   

Abstract

Magnetic resonance spectroscopy (MRS) provides a noninvasive measurement of the biochemistry of living tissue. We report spectroscopy analysis of a 26-year-old woman affected by right ovarian lesion diagnosed as mucinous cystadenoma. MRS was performed by the point-resolved spectroscopy technique with a long echo time (TE) (136 msec). MRS measurements were performed on the two distinct component of the right ovarian tumor. The classification of metabolite peaks area in this study was performed according to the technique described by Okada et al. The features of proton MRS studies are discussed. As well as strongly elevated lactate and N-acetyl-L-aspartate signals, the tumor spectrum showed lipid resonances. Proton MRS imaging may be helpful for the investigation of the underlying pathophysiology of ovarian mucinous cystadenomas.

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Year:  2006        PMID: 16445669     DOI: 10.1111/j.1525-1438.2006.00200.x

Source DB:  PubMed          Journal:  Int J Gynecol Cancer        ISSN: 1048-891X            Impact factor:   3.437


  9 in total

1.  N-acetyl peak in proton MR spectroscopy of metastatic mucinous adenocarcinoma of brain.

Authors:  Z Abdul Aziz; D Jethwani; G Ananta Ram; G G Sharath Kumar; J Saini
Journal:  Clin Neuroradiol       Date:  2012-02-25       Impact factor: 3.649

2.  Cancer-Specific Production of N-Acetylaspartate via NAT8L Overexpression in Non-Small Cell Lung Cancer and Its Potential as a Circulating Biomarker.

Authors:  Tzu-Fang Lou; Deepa Sethuraman; Patrick Dospoy; Pallevi Srivastva; Hyun Seok Kim; Joongsoo Kim; Xiaotu Ma; Pei-Hsuan Chen; Kenneth E Huffman; Robin E Frink; Jill E Larsen; Cheryl Lewis; Sang-Won Um; Duk-Hwan Kim; Jung-Mo Ahn; Ralph J DeBerardinis; Michael A White; John D Minna; Hyuntae Yoo
Journal:  Cancer Prev Res (Phila)       Date:  2015-10-28

3.  Preliminary observations and clinical value of N-acetyl resonances in ovarian tumours using in-vivo proton MR spectroscopy at 3T.

Authors:  Mayumi Takeuchi; Kenji Matsuzaki; Masafumi Harada
Journal:  Eur Radiol       Date:  2011-08-05       Impact factor: 5.315

4.  Role of MR spectroscopy in diagnosis of intracranial neuroenteric cyst.

Authors:  R V Phadke; Suprava Naik; Alok Udiya; Gurucharan S Shetty; Vivek Singh; Sanjeev Kumar Bhoi
Journal:  Childs Nerv Syst       Date:  2018-04-20       Impact factor: 1.475

5.  RhoC GTPase Is a Potent Regulator of Glutamine Metabolism and N-Acetylaspartate Production in Inflammatory Breast Cancer Cells.

Authors:  Michelle L Wynn; Joel A Yates; Charles R Evans; Lauren D Van Wassenhove; Zhi Fen Wu; Sydney Bridges; Liwei Bao; Chelsea Fournier; Sepideh Ashrafzadeh; Matthew J Merrins; Leslie S Satin; Santiago Schnell; Charles F Burant; Sofia D Merajver
Journal:  J Biol Chem       Date:  2016-04-25       Impact factor: 5.157

6.  Identification of metabolites in the normal ovary and their transformation in primary and metastatic ovarian cancer.

Authors:  Miranda Y Fong; Jonathan McDunn; Sham S Kakar
Journal:  PLoS One       Date:  2011-05-19       Impact factor: 3.240

7.  Metabolomic Characterization of Ovarian Epithelial Carcinomas by HRMAS-NMR Spectroscopy.

Authors:  D Ben Sellem; K Elbayed; A Neuville; F-M Moussallieh; G Lang-Averous; M Piotto; J-P Bellocq; I J Namer
Journal:  J Oncol       Date:  2011-04-26       Impact factor: 4.375

8.  Bridging the gap between non-targeted stable isotope labeling and metabolic flux analysis.

Authors:  Daniel Weindl; Thekla Cordes; Nadia Battello; Sean C Sapcariu; Xiangyi Dong; Andre Wegner; Karsten Hiller
Journal:  Cancer Metab       Date:  2016-04-23

Review 9.  N-Acetylaspartate Metabolism Outside the Brain: Lipogenesis, Histone Acetylation, and Cancer.

Authors:  Juliane G Bogner-Strauss
Journal:  Front Endocrinol (Lausanne)       Date:  2017-09-20       Impact factor: 5.555

  9 in total

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