| Literature DB >> 164454 |
K Minton, M Durphy, R Taylor, E C Friedberg.
Abstract
The T4 ultraviolet endonuclease was previously shown to produce strand incisions (nicks) in ultraviolet-irradiated DNA on the 5' side of thymine dimers. The present studies demonstrate that the purified endonuclease creates 3'-OH and 5'-P termini at the sites of nicking. Photoreactivation of ultraviolet-sensitive sites, thereby demonstrating directly endonucleause has a molecular weight of approximately 18,000 and attacks ultraviolet-irradiated single-stranded Escherichia coli and M-13 DNA.Entities:
Mesh：
Substances：
Year: 1975 PMID： 164454
Source DB: PubMed Journal: J Biol Chem ISSN： 0021-9258 Impact factor: 5.157