| Literature DB >> 16444961 |
Asako Kitano1, Koh Yamamoto, Toshikage Nagao, Minako Yoshida, Tetsuya Kurosu, Ayako Arai, Tohru Miki, Naomi Murakami, Osamu Miura.
Abstract
A 53-year-old male was admitted because of pancytopenia and chronic subdural hematoma. Bone marrow was hypercellular with 97% blasts, which expressed CD10, CD19, CD20, and immunoglobulin mu and gamma chains on the cell surface and had chromosomal abnormalities including t(8 ; 22)(q24 ; q11). The patient was diagnosed as having Burkitt leukemia. Because hemiplegia and disturbance of consciousness developed rapidly, the patient was treated with an emergency drainage operation followed by Hyper-CVAD therapy and achieved a sustained complete remission. Dural infiltration of leukemic cells as well as thrombocytopenia was implicated in the pathogenesis of the subdural hematoma, which contained numerous blasts.Entities:
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Year: 2005 PMID: 16444961
Source DB: PubMed Journal: Rinsho Ketsueki ISSN: 0485-1439