Literature DB >> 16443488

Neuropathology of Alzheimer's disease.

Ryan T Mott1, Christine M Hulette.   

Abstract

In 1907, Alois Alzheimer described the presence of plaques and neurofibrillary tangles in a demented patient. Currently, Alzheimer's disease is known to be the most common cause of dementia in elderly patients. In this article, we summarize the most important neuropathologic features of Alzheimer's disease, including amyloid plaques, neurofibrillary tangles, neuronal loss, synaptic depletion, cerebral amyloid angiopathy, Hirano bodies, and granulovacuolar degeneration. We also review the history and application of Alzheimer's disease diagnostic criteria.

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Year:  2005        PMID: 16443488     DOI: 10.1016/j.nic.2005.09.003

Source DB:  PubMed          Journal:  Neuroimaging Clin N Am        ISSN: 1052-5149            Impact factor:   2.264


  18 in total

Review 1.  Multimodality Review of Amyloid-related Diseases of the Central Nervous System.

Authors:  Michelle M Miller-Thomas; Adam L Sipe; Tammie L S Benzinger; Jonathan McConathy; Sarah Connolly; Katherine E Schwetye
Journal:  Radiographics       Date:  2016 Jul-Aug       Impact factor: 5.333

Review 2.  Mechanisms of mononuclear phagocyte recruitment in Alzheimer's disease.

Authors:  Suzanne E Hickman; Joseph El Khoury
Journal:  CNS Neurol Disord Drug Targets       Date:  2010-04       Impact factor: 4.388

3.  [Clinically validated molecular biomarkers of neurodegenerative dementia].

Authors:  J Wiltfang
Journal:  Nervenarzt       Date:  2014-11       Impact factor: 1.214

Review 4.  Multiphoton in vivo imaging of amyloid in animal models of Alzheimer's disease.

Authors:  Jinghui Dong; Raquel Revilla-Sanchez; Stephen Moss; Philip G Haydon
Journal:  Neuropharmacology       Date:  2010-04-14       Impact factor: 5.250

5.  Aβ Plaques.

Authors:  Lary C Walker
Journal:  Free Neuropathol       Date:  2020-10-30

6.  Subjective cognition and amyloid deposition imaging: a Pittsburgh Compound B positron emission tomography study in normal elderly individuals.

Authors:  Audrey Perrotin; Elizabeth C Mormino; Cindee M Madison; Amynta O Hayenga; William J Jagust
Journal:  Arch Neurol       Date:  2012-02

7.  Cardiovascular dementia - a different perspective.

Authors:  Udhaya Kumari; Klaus Heese
Journal:  Open Biochem J       Date:  2010-03-26

8.  Microglial dysfunction and defective beta-amyloid clearance pathways in aging Alzheimer's disease mice.

Authors:  Suzanne E Hickman; Elizabeth K Allison; Joseph El Khoury
Journal:  J Neurosci       Date:  2008-08-13       Impact factor: 6.167

Review 9.  Neuropathology for the neuroradiologist: plaques and tangles.

Authors:  F J Wippold; N Cairns; K Vo; D M Holtzman; J C Morris
Journal:  AJNR Am J Neuroradiol       Date:  2007-10-09       Impact factor: 3.825

10.  Development of photocrosslinked sialic acid containing polymers for use in Abeta toxicity attenuation.

Authors:  Christopher B Cowan; Gerard L Coté; Theresa A Good
Journal:  Biomaterials       Date:  2008-06-03       Impact factor: 12.479

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