Ákos Somoskövi1, Zoltán Bártfai2, Lilla Tamási2, Judit Kocsis3, Erzsébet Puhó4, Andrew E Czeizel5. 1. Department of Respiratory Medicine, School of Medicine, Semmelweis University, 1536 Budapest 114, P.O. Box 250, Budapest, Hungary. Electronic address: akos@pulm.sote.hu. 2. Department of Respiratory Medicine, School of Medicine, Semmelweis University, 1536 Budapest 114, P.O. Box 250, Budapest, Hungary. 3. III Department of Internal Medicine, School of Medicine, Semmelweis University, Budapest, Hungary. 4. National Institute for Epidemiology, Department of Human Genetics and Teratology, Budapest, Hungary; Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary. 5. Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary.
Abstract
OBJECTIVE: Allergic rhinitis is frequent in women of childbearing age including pregnancy. The present study aimed to estimate the effect of maternal allergic rhinitis on birth outcomes, in particular congenital abnormalities, preterm birth and low birthweight newborns. STUDY DESIGN: Analysis of the population-based data of the Hungarian Case-Control Surveillance of Congenital Abnormalities between 1980 and 1996. RESULTS: The evaluation of data did not reveal any teratogenic potential of allergic rhinitis and indeed a lower prevalence of total congenital abnormalities was found. In addition, a protective effect could be observed for preterm birth due to longer gestational age (adjusted t=2.97, p=0.003). CONCLUSION: Allergic rhinitis is not risk factor for pregnant women.
OBJECTIVE:Allergic rhinitis is frequent in women of childbearing age including pregnancy. The present study aimed to estimate the effect of maternal allergic rhinitis on birth outcomes, in particular congenital abnormalities, preterm birth and low birthweight newborns. STUDY DESIGN: Analysis of the population-based data of the Hungarian Case-Control Surveillance of Congenital Abnormalities between 1980 and 1996. RESULTS: The evaluation of data did not reveal any teratogenic potential of allergic rhinitis and indeed a lower prevalence of total congenital abnormalities was found. In addition, a protective effect could be observed for preterm birth due to longer gestational age (adjusted t=2.97, p=0.003). CONCLUSION:Allergic rhinitis is not risk factor for pregnant women.