Literature DB >> 16442361

Impact of clopidogrel on suppression of circulating levels of soluble CD40 ligand in patients with unstable angina undergoing coronary stenting.

Hon-Kan Yip1, Li-Teh Chang, Cheuk-Kwan Sun, Cheng-Hsu Yang, Wei-Chin Hung, Cheng-I Cheng, Sarah Chua, Kuo-Ho Yeh, Chiung-Jen Wu, Morgan Fu.   

Abstract

This study investigated whether a regimen that comprised a loading dose of 300 mg of clopidogrel followed by 75 mg/day could significantly suppress circulating levels of soluble CD40 ligand (sCD40L) in patients who had unstable angina and underwent coronary stenting. Study results showed that the clopidogrel loading dose substantially decreased the circulating level of sCD40L at 24 hours after stenting (p <0.0001). Combined with aspirin, 75 mg/day of clopidogrel continuously decreased sCD40L levels after coronary stenting.

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Year:  2005        PMID： 16442361     DOI： 10.1016/j.amjcard.2005.08.023

Source DB:  PubMed          Journal:  Am J Cardiol        ISSN： 0002-9149            Impact factor:   2.778


  7 in total

Review 1.  CD40/CD40L system and vascular disease.

Authors:  F Santilli; S Basili; P Ferroni; G Davì
Journal:  Intern Emerg Med       Date:  2007-11-28       Impact factor: 3.397

2.  PROCLAIM: pilot study to examine the effects of clopidogrel on inflammatory markers in patients with metabolic syndrome receiving low-dose aspirin.

Authors:  James T Willerson; Greg Cable; Edward T H Yeh
Journal:  Tex Heart Inst J       Date:  2009

3.  Clopidogrel for the hot patient.

Authors:  Matthew L Bilodeau; Daniel I Simon
Journal:  Circ Cardiovasc Interv       Date:  2009-12       Impact factor: 6.546

4.  Combination of cilostazol and clopidogrel attenuates rat critical limb ischemia.

Authors:  Jiunn-Jye Sheu; Kun-Chen Lin; Ching-Yen Tsai; Tzu-Hsien Tsai; Steve Leu; Chia-Hung Yen; Yung-Lung Chen; Hsueh-Wen Chang; Cheuk-Kwan Sun; Sarah Chua; Jenq-Lin Yang; Hon-Kan Yip
Journal:  J Transl Med       Date:  2012-08-16       Impact factor: 5.531

5.  Effect of clopidogrel discontinuation at 1 year after drug eluting stent placement on soluble CD40L, P-selectin and C-reactive protein levels: DECADES (Discontinuation Effect of Clopidogrel After Drug Eluting Stent): a multicenter, open-label study.

Authors:  Joanna J Wykrzykowska; Ascan Warnholtz; Peter de Jaeger; Nick Curzen; Keith G Oldroyd; Jean Philippe Collet; Jurrien M Ten Berg; Tessa Rademaker; Dick Goedhart; Jurgen Lissens; Peter-Paul Kint; Patrick W Serruys
Journal:  J Thromb Thrombolysis       Date:  2009-11       Impact factor: 2.300

6.  Soluble CD40 Ligand in Aspirin-Treated Patients Undergoing Cardiac Catheterization.

Authors:  Thomas Gremmel; Andrew L Frelinger; Alan D Michelson
Journal:  PLoS One       Date:  2015-08-03       Impact factor: 3.240

7.  Platelet CD40 ligand and bleeding during P2Y12 inhibitor treatment in acute coronary syndrome.

Authors:  Charlotte Grosdidier; Kelly D Blanz; Pierre Deharo; Denis Bernot; Marjorie Poggi; Delphine Bastelica; Dennis Wolf; Daniel Duerschmied; Michel Grino; Thomas Cuisset; Marie-Christine Alessi; Matthias Canault
Journal:  Res Pract Thromb Haemost       Date:  2019-07-26
  7 in total

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