Literature DB >> 16442300

The effect of Ge, Si and Sn phthalocyanine photosensitizers on cell proliferation and viability of human oesophageal carcinoma cells.

Itumeleng Seotsanyana-Mokhosi1, Tina Kresfelder, Heidi Abrahamse, Tebello Nyokong.   

Abstract

The photodynamic activity of water soluble mixed sulfonated metallophthalocyanines complexes: GePcSmix, SnPcSmix and SiPcSmix on human oesophageal carcinoma (SNO) cells are reported, and compared with the activity of the unmetallated H2PcSmix and of the newly synthesized water soluble adjacently substituted binaphthalo phthalocyanine (complex 3). The alkaline phosphate (ALP) showed damage to the cell membrane in the presence of complex 3 without irradiation. The GePcSmix complex caused a relatively large increase in inflammation and a high intracellular ATP.

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Year:  2006        PMID： 16442300     DOI： 10.1016/j.jphotobiol.2005.12.004

Source DB:  PubMed          Journal:  J Photochem Photobiol B        ISSN： 1011-1344            Impact factor:   6.252


  5 in total

1.  Effect of a newly synthesized Zn sulfophthalocyanine derivative on cell morphology, viability, proliferation, and cytotoxicity in a human lung cancer cell line (A549).

Authors:  Sello Lebohang Manoto; Heidi Abrahamse
Journal:  Lasers Med Sci       Date:  2011-01-29       Impact factor: 3.161

Review 2.  Like a bolt from the blue: phthalocyanines in biomedical optics.

Authors:  Nawal Sekkat; Hubert van den Bergh; Tebello Nyokong; Norbert Lange
Journal:  Molecules       Date:  2011-12-23       Impact factor: 4.411

3.  Resistance of lung cancer cells grown as multicellular tumour spheroids to zinc sulfophthalocyanine photosensitization.

Authors:  Sello Lebohang Manoto; Nicolette Nadene Houreld; Heidi Abrahamse
Journal:  Int J Mol Sci       Date:  2015-05-05       Impact factor: 5.923

Review 4.  Cell death pathways and phthalocyanine as an efficient agent for photodynamic cancer therapy.

Authors:  Ivan Mfouo-Tynga; Heidi Abrahamse
Journal:  Int J Mol Sci       Date:  2015-05-06       Impact factor: 5.923

Review 5.  Phthalocyanine and Its Formulations: A Promising Photosensitizer for Cervical Cancer Phototherapy.

Authors:  Lucimara R Carobeli; Lyvia E de F Meirelles; Gabrielle M Z F Damke; Edilson Damke; Maria V F de Souza; Natália L Mari; Kayane H Mashiba; Cristiane S Shinobu-Mesquita; Raquel P Souza; Vânia R S da Silva; Renato S Gonçalves; Wilker Caetano; Márcia E L Consolaro
Journal:  Pharmaceutics       Date:  2021-12-02       Impact factor: 6.321
  5 in total

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