Literature DB >> 1644192

Ubiquinone biosynthesis. Cloning of the genes coding for chorismate pyruvate-lyase and 4-hydroxybenzoate octaprenyl transferase from Escherichia coli.

M Siebert1, A Bechthold, M Melzer, U May, U Berger, G Schröder, J Schröder, K Severin, L Heide.   

Abstract

Chorismate pyruvate-lyase activity was detected in extracts of Escherichia coli. 4-Hydroxybenzoate was identified as the product of the enzymatic reaction by chemical derivatization and GC-MS analysis. The ubiC gene, coding for the chorismate pyruvate-lyase, was cloned and sequenced. The molecular weight of the gene product was calculated as 18,776 Da and confirmed by expression of the protein in E. coli minicells. The ubiA gene, coding for the 4-hydroxybenzoate octaprenyl transferase, was identified by sequence homology and complementation of a ubiA- strain. It is located directly downstream of ubiC in a typical operon structure.

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Year:  1992        PMID： 1644192     DOI： 10.1016/0014-5793(92)80710-x

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  21 in total

1.  A C-methyltransferase involved in both ubiquinone and menaquinone biosynthesis: isolation and identification of the Escherichia coli ubiE gene.

Authors:  P T Lee; A Y Hsu; H T Ha; C F Clarke
Journal:  J Bacteriol       Date:  1997-03       Impact factor: 3.490

2.  Modeling the E. coli 4-hydroxybenzoic acid oligoprenyltransferase ( ubiA transferase) and characterization of potential active sites.

Authors:  Lars Bräuer; Wolfgang Brandt; Ludger A Wessjohann
Journal:  J Mol Model       Date:  2004-08-27       Impact factor: 1.810

3.  Genetic engineering of shikonin biosynthesis hairy root cultures of Lithospermum erythrorhizon transformed with the bacterial ubiC gene.

Authors:  S Sommer; A Köhle; K Yazaki; K Shimomura; A Bechthold; L Heide
Journal:  Plant Mol Biol       Date:  1999-03       Impact factor: 4.076

4.  Genetic engineering of plant secondary metabolism. Accumulation of 4-hydroxybenzoate glucosides as a result of the expression of the bacterial ubiC gene in tobacco.

Authors:  M Siebert; S Sommer; S M Li; Z X Wang; K Severin; L Heide
Journal:  Plant Physiol       Date:  1996-10       Impact factor: 8.340

5.  Clarification of the Escherichia coli genetic map in the 92-minute region containing the ubiCA operon and the plsB, dgk, lexA, and dinF genes.

Authors:  L Heide; M Melzer; M Siebert; A Bechthold; J Schröder; K Severin
Journal:  J Bacteriol       Date:  1993-09       Impact factor: 3.490

6.  Ubiquinone-10 production using Agrobacterium tumefaciens dps gene in Escherichia coli by coexpression system.

Authors:  Dawei Zhang; Binaya Shrestha; Zhaopeng Li; Tianwei Tan
Journal:  Mol Biotechnol       Date:  2007-01       Impact factor: 2.695

7.  Characterization of composite aminodeoxyisochorismate synthase and aminodeoxyisochorismate lyase activities of anthranilate synthase.

Authors:  A A Morollo; R Bauerle
Journal:  Proc Natl Acad Sci U S A       Date:  1993-11-01       Impact factor: 11.205

Review 8.  Functions of the gene products of Escherichia coli.

Authors:  M Riley
Journal:  Microbiol Rev       Date:  1993-12

9.  The pds2 mutation is a lesion in the Arabidopsis homogentisate solanesyltransferase gene involved in plastoquinone biosynthesis.

Authors:  Li Tian; Dean DellaPenna; Richard A Dixon
Journal:  Planta       Date:  2007-06-14       Impact factor: 4.116

10.  Microbial production of specifically ring-13C-labelled 4-hydroxybenzoic acid.

Authors:  R Müller; A Wagener; K Schmidt; E Leistner
Journal:  Appl Microbiol Biotechnol       Date:  1995-11       Impact factor: 4.813
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