Literature DB >> 16441361

Impact of biliary complications in right lobe living donor liver transplantation.

Giovanni Ramacciato1, Giovanni Varotti, Cristiano Quintini, Michele Masetti, Fabrizio Di Benedetto, Gian Luca Grazi, Giorgio Ercolani, Matteo Cescon, Matteo Ravaioli, Augusto Lauro, Antonio Pinna.   

Abstract

Biliary reconstruction is one of the most challenging parts of right lobe living donor liver transplantation (RL LDLT), and biliary complications have been reported as the first source of surgical complications of this procedure. We reviewed biliary reconstruction and complications in 27 consecutive RL LDLTs. We compared the first 14 procedures (group 1) to the last 13 (group 2). Seven patients (25.9%) experienced a biliary complication (five leaks and two strictures). The incidence of biliary complications was 11.1% in RL grafts with a single duct and 55.5% in graft presenting multiple bile ducts (P = 0.03). Four of the 18 patients with a duct-to-duct reconstruction (22.2%) and three of the 11 patients with a Roux-en-Y reconstruction (27.3%) developed a biliary complication (P = ns). The incidence of biliary complications significantly decreased from 42.9% (n = 6) in the first group to 7.6% (n = 1) in the second group (P = 0.05). The overall 1-year graft and patient survival were 57.1% and 64.3% in group 1 versus 100.0% and 100% in group 2 (P = 0.01; P = 0.006). Biliary complications remain one of the most important technical complications affecting RL LDLT. Nevertheless, attention and surgical refinement can lead to a significant reduction of the biliary complication rate, improving graft and patient survival.

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Year:  2006        PMID: 16441361     DOI: 10.1111/j.1432-2277.2005.00248.x

Source DB:  PubMed          Journal:  Transpl Int        ISSN: 0934-0874            Impact factor:   3.782


  8 in total

1.  Intraoperative real-time cholangiography and C-tube drainage in donor hepatectomy reduce biliary tract complications.

Authors:  Toshiya Ochiai; Hisashi Ikoma; Koji Inoue; Yasutoshi Murayama; Shuhei Komatsu; Atsushi Shiozaki; Yoshiaki Kuriu; Masayoshi Nakanishi; Daisuke Ichikawa; Hitoshi Fujiwara; Kazuma Okamoto; Yukihito Kokuba; Teruhisa Sonoyama; Eigo Otsuji
Journal:  J Gastrointest Surg       Date:  2011-09-29       Impact factor: 3.452

Review 2.  Biliary complications in living liver donors.

Authors:  Yufeng Yuan; Mitsukazu Gotoh
Journal:  Surg Today       Date:  2010-04-28       Impact factor: 2.549

3.  Biliary complications after adult to adult right-lobe living donor liver transplantation (A-ARLLDLT): Analysis of 245 cases during 16 years period at a single high centre- A retrospective cohort study.

Authors:  Emad Hamdy Gad; Eslam Ayoup; Amr M Aziz; Tarek Ibrahim; Mostafa Elhelbawy; Mohammed Al-Sayed Abd-Elsamee; Ahmed Nabil Sallam
Journal:  Ann Med Surg (Lond)       Date:  2022-04-14

Review 4.  Advances in endoscopic management of biliary complications after living donor liver transplantation: Comprehensive review of the literature.

Authors:  Milljae Shin; Jae-Won Joh
Journal:  World J Gastroenterol       Date:  2016-07-21       Impact factor: 5.742

5.  Alternative techniques for cannulation of biliary strictures resistant to the 0.035" system following living donor liver transplantation.

Authors:  Hee Mang Yoon; Jin Hyoung Kim; Gi-Young Ko; Ho-Young Song; Dong Il Gwon; Kyu-Bo Sung
Journal:  Korean J Radiol       Date:  2012-03-07       Impact factor: 3.500

6.  Massive biloma presenting as gastric outlet obstruction.

Authors:  Emmanuel C Gorospe; Cadman L Leggett; Nikhil A Nadkarni
Journal:  Ann Gastroenterol       Date:  2012

7.  Comparison of different magnetic resonance cholangiography techniques in living liver donors including Gd-EOB-DTPA enhanced T1-weighted sequences.

Authors:  Sonja Kinner; Verena Steinweg; Stefan Maderwald; Arnold Radtke; Georgios Sotiropoulos; Michael Forsting; Tobias Schroeder
Journal:  PLoS One       Date:  2014-11-26       Impact factor: 3.240

8.  Endoscopic therapy for biliary strictures complicating living donor liver transplantation: Factors predicting better outcome.

Authors:  Harshavardhan B Rao; Hasim Ahamed; Suprabha Panicker; Surendran Sudhindran; Rama P Venu
Journal:  World J Gastrointest Pathophysiol       Date:  2017-05-15
  8 in total

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