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Literature DB >> 16441085

Cyclohaliclonamines A-E: dimeric, trimeric, tetrameric, pentameric, and hexameric 3-alkyl pyridinium alkaloids from a marine sponge Haliclona sp.

Toshiaki Teruya¹, Keiko Kobayashi, Kiyotake Suenaga, Hideo Kigoshi.

Abstract

A mixture of cyclohaliclonamines A-E (1-5), novel dimeric, trimeric, tetrameric, pentameric, and hexameric 3-alkylpyridinium alkaloids, was obtained from an Okinawan sponge Haliclona sp. Cyclohaliclonamines C-E are the first tetrameric, pentameric, and hexameric 3-alkylpyridinium alkaloids from natural sources. The structure determination of cyclohaliclonamines is discussed in detail.

Entities: Chemical Species

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Year: 2006 PMID： 16441085 DOI： 10.1021/np050308+

Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050

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Cited

6 in total

Review 1. Synthesis of 3-alkyl pyridinium alkaloids from the arctic sponge Haliclona viscosa.

Authors: Christoph Timm; Thorsten Mordhorst; Matthias Köck
Journal: Mar Drugs Date: 2010-03-05 Impact factor: 5.118

2. An Efficient Synthesis of 3-Alkylpyridine Alkaloids Enables Their Biological Evaluation.

Authors: Anna R Kaplan; Cassandra L Schrank; William M Wuest
Journal: ChemMedChem Date: 2021-04-14 Impact factor: 3.540

3. Metabolic Profiling as a Screening Tool for Cytotoxic Compounds: Identification of 3-Alkyl Pyridine Alkaloids from Sponges Collected at a Shallow Water Hydrothermal Vent Site North of Iceland.

Authors: Eydis Einarsdottir; Manuela Magnusdottir; Giuseppe Astarita; Matthias Köck; Helga M Ögmundsdottir; Margret Thorsteinsdottir; Hans Tore Rapp; Sesselja Omarsdottir; Giuseppe Paglia
Journal: Mar Drugs Date: 2017-02-22 Impact factor: 5.118

Cyclohaliclonamines A-E: dimeric, trimeric, tetrameric, pentameric, and hexameric 3-alkyl pyridinium alkaloids from a marine sponge Haliclona sp.

Review 1. Synthesis of 3-alkyl pyridinium alkaloids from the arctic sponge Haliclona viscosa.

2. An Efficient Synthesis of 3-Alkylpyridine Alkaloids Enables Their Biological Evaluation.

3. Metabolic Profiling as a Screening Tool for Cytotoxic Compounds: Identification of 3-Alkyl Pyridine Alkaloids from Sponges Collected at a Shallow Water Hydrothermal Vent Site North of Iceland.

4. Sponge chemical defenses are a possible mechanism for increasing sponge abundance on reefs in Zanzibar.

Review 5. Bioactive Nitrogenous Secondary Metabolites from the Marine Sponge Genus Haliclona.

6. Mechanisms of toxicity of 3-alkylpyridinium polymers from marine sponge Reniera sarai.