Literature DB >> 16440834

A note on ethnic sensitivity studies.

Michaela Glasbrenner1, Gerd Rosenkranz.   

Abstract

In this article, we propose a similarity criterion for ethnic sensitivity studies in pharmacokinetic variables. We present how this criterion can be used in the context of different dose-exposure models and how sample size and power calculations can be done. Examples for the planning and analysis of ethnic sensitivity studies are provided.

Mesh:

Year:  2006        PMID: 16440834     DOI: 10.1080/10543400500406454

Source DB:  PubMed          Journal:  J Biopharm Stat        ISSN: 1054-3406            Impact factor:   1.051


  1 in total

1.  Efficacy, safety and pharmacokinetics of indacaterol in Caucasian and Japanese patients with chronic obstructive pulmonary disease: a comparison of data from two randomized, placebo-controlled studies.

Authors:  Motoi Hosoe; Ralph Woessner; Soichiro Matsushima; David Lawrence; Benjamin Kramer
Journal:  Clin Drug Investig       Date:  2011       Impact factor: 2.859

  1 in total

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