Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Biochemistry. Loop grafting and the origins of enzyme species.

× No keyword cloud information.

19 in total

1. A portable hot spot recognition loop transfers sequence preferences from APOBEC family members to activation-induced cytidine deaminase.

Authors: Rahul M Kohli; Shaun R Abrams; Kiran S Gajula; Robert W Maul; Patricia J Gearhart; James T Stivers
Journal: J Biol Chem Date: 2009-06-26 Impact factor: 5.157

2. Novel mutation in Cul7 gene in a family diagnosed with 3M syndrome.

Authors: Shagufta Shaikh; Suresh K G Shettigar; Santosh Kumar; Surita Kantharia; Jagannath Kurva; Susan Cherian
Journal: J Genet Date: 2019-03 Impact factor: 1.166

3. Highly diverse protein library based on the ubiquitous (β/α)₈ enzyme fold yields well-structured proteins through in vitro folding selection.

Authors: Misha V Golynskiy; John C Haugner; Burckhard Seelig
Journal: Chembiochem Date: 2013-08-16 Impact factor: 3.164

4. Evolution to carbapenem-hydrolyzing activity in noncarbapenemase class D β-lactamase OXA-10 by rational protein design.

Authors: Filomena De Luca; Manuela Benvenuti; Filippo Carboni; Cecilia Pozzi; Gian Maria Rossolini; Stefano Mangani; Jean-Denis Docquier
Journal: Proc Natl Acad Sci U S A Date: 2011-10-31 Impact factor: 11.205

Biochemistry. Loop grafting and the origins of enzyme species.

1. A portable hot spot recognition loop transfers sequence preferences from APOBEC family members to activation-induced cytidine deaminase.

2. Novel mutation in Cul7 gene in a family diagnosed with 3M syndrome.

3. Highly diverse protein library based on the ubiquitous (β/α)₈ enzyme fold yields well-structured proteins through in vitro folding selection.

4. Evolution to carbapenem-hydrolyzing activity in noncarbapenemase class D β-lactamase OXA-10 by rational protein design.

5. Directed evolution of a thermostable quorum-quenching lactonase from the amidohydrolase superfamily.

Review 6. Enzyme (re)design: lessons from natural evolution and computation.

7. Role of the NC-loop in catalytic activity and stability in lipase from Fervidobacterium changbaicum.

8. Exploring the evolution of novel enzyme functions within structurally defined protein superfamilies.

Review 9. Why reinvent the wheel? Building new proteins based on ready-made parts.

10. How protein stability and new functions trade off.