| Literature DB >> 16439197 |
Abstract
Immune evasion by the malaria parasite Plasmodium falciparum is mediated by the mutually exclusive expression of a single member of the var family of genes, which encode variant surface antigens. In a recent paper in Nature, demonstrate that a construct carrying a transcriptionally active var promoter is sufficient to promote allelic exclusion of the parasite's endogenous var gene.Entities:
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Year: 2006 PMID： 16439197 DOI： 10.1016/j.cell.2006.01.004
Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582