Literature DB >> 16437700

Recurrent severe gastrointestinal bleeding and malabsorption due to extensive habitual megacolon.

Ingo Mecklenburg1, Markus Leibig, Christof Weber, Stefan Schmidbauer, Christian Folwaczny.   

Abstract

Dilatation of the colon and the rectum, which is not attributable to aganglionosis, is a rare finding and can be the result of intractable chronic constipation. We report a rare case of a 29-year-old male patient with impressive megacolon, in whom Hirschsprung's or Chagas disease was ruled out. In the present case, dilatation of the colon was most likely due to a behavioral disorder with habitual failure of defecation. Chronic stool retention led to a bizarre bulging of the large bowel with displacement of the other abdominal organs and severe occult blood loss. Because of two episodes of life-threatening gastrointestinal bleeding despite conventional treatment of constipation, a surgical approach for bowel restoration was necessary. Temporary loop ileostomy had to be performed for de-pressurization of the large bowel and the subsequent possibility for effective antegrade colonic lavage to remove impacted stools. Shortly after the operation, the patient was healthy and could easily manage the handling of the ileostomy. However, the course of the megacolon in this young adult cannot be predicted and the follow-up will have to reveal if regression of this extreme colonic distension with reestablishment of regular rectal perception will occur.

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Year:  2005        PMID: 16437700      PMCID: PMC4727221          DOI: 10.3748/wjg.v11.i48.7686

Source DB:  PubMed          Journal:  World J Gastroenterol        ISSN: 1007-9327            Impact factor:   5.742


  5 in total

1.  Chagasic megacolon and proximal jejunum microbiota.

Authors:  A G Guimarães Quintanilha; M A Azevedo dos Santos; M J Avila-Campos; W A Saad; H W Pinotti; B Zilberstein
Journal:  Scand J Gastroenterol       Date:  2000-06       Impact factor: 2.423

Review 2.  Giant fecaloma with idiopathic sigmoid megacolon: report of a case and review of the literature.

Authors:  Ambil Rajagopal; Joseph Martin
Journal:  Dis Colon Rectum       Date:  2002-06       Impact factor: 4.585

Review 3.  Pathogenesis of Hirschsprung's disease and its variants: recent progress.

Authors:  Prem Puri; Toko Shinkai
Journal:  Semin Pediatr Surg       Date:  2004-02       Impact factor: 2.754

Review 4.  Diversion colitis--new light through old windows.

Authors:  C M Edwards; B George; B Warren
Journal:  Histopathology       Date:  1999-01       Impact factor: 5.087

5.  Results of stoma formation for idiopathic megarectum and megacolon.

Authors:  G Stabile; M A Kamm; P R Hawley; J E Lennard-Jones
Journal:  Int J Colorectal Dis       Date:  1992-06       Impact factor: 2.571

  5 in total
  2 in total

1.  Therapeutic effect of orally administered microencapsulated oxaliplatin for colorectal cancer.

Authors:  Aleksandra M Urbanska; Emmanouil D Karagiannis; Gonzalo Guajardo; Robert S Langer; Daniel G Anderson
Journal:  Biomaterials       Date:  2012-04-01       Impact factor: 12.479

2.  Adult patients with allied disorders of Hirschsprung's disease in emergency department: An 11-year retrospective study.

Authors:  Shuai Jiang; Cong-Ying Song; Meng-Xiao Feng; Yuan-Qiang Lu
Journal:  World J Gastrointest Surg       Date:  2022-07-27
  2 in total

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